The gut microbiome and hypertension
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …
microbiome in the regulation of blood pressure. The field has moved from association to …
Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy
C Campbell, MR Kandalgaonkar, RM Golonka… - Biomedicines, 2023 - mdpi.com
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …
of host immunity, which can influence disease susceptibility. Herein, we review the most …
[HTML][HTML] Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension
S Jiang, Y Shui, Y Cui, C Tang, X Wang, X Qiu, W Hu… - Redox biology, 2021 - Elsevier
Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary
phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the …
phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the …
[HTML][HTML] Diet-gut microbiota interactions on cardiovascular disease
X Zhang, P Gérard - Computational and structural biotechnology journal, 2022 - Elsevier
Cardiovascular diseases (CVD) are a group of disorders of the heart and blood vessels and
remain the leading cause of morbidity and mortality worldwide. Over the past decades …
remain the leading cause of morbidity and mortality worldwide. Over the past decades …
Toward precision medicine: circadian rhythm of blood pressure and chronotherapy for hypertension-2021 NHLBI workshop report
Healthy individuals exhibit blood pressure variation over a 24-hour period with higher blood
pressure during wakefulness and lower blood pressure during sleep. Loss or disruption of …
pressure during wakefulness and lower blood pressure during sleep. Loss or disruption of …
Probiotics: Protecting our health from the gut
GU Varela-Trinidad, C Domínguez-Díaz… - Microorganisms, 2022 - mdpi.com
The gut microbiota (GM) comprises billions of microorganisms in the human gastrointestinal
tract. This microbial community exerts numerous physiological functions. Prominent among …
tract. This microbial community exerts numerous physiological functions. Prominent among …
Identification of a gut commensal that compromises the blood pressure-lowering effect of ester angiotensin-converting enzyme inhibitors
Background: Despite the availability of various classes of antihypertensive medications, a
large proportion of hypertensive individuals remain resistant to treatments. The reason for …
large proportion of hypertensive individuals remain resistant to treatments. The reason for …
Short-chain fatty acid receptors and blood pressure regulation: council on hypertension mid-career award for research excellence 2021
The gut microbiome influences host physiology and pathophysiology through several
pathways, one of which is microbial production of chemical metabolites which interact with …
pathways, one of which is microbial production of chemical metabolites which interact with …
Role of the microbiota in hypertension and antihypertensive drug metabolism
E Mishima, T Abe - Hypertension Research, 2022 - nature.com
Recent evidence suggests that the gut microbiota plays an important role in the
development and pathogenesis of hypertension. Dysbiosis, an imbalance in the composition …
development and pathogenesis of hypertension. Dysbiosis, an imbalance in the composition …
The impact of gut microbiota metabolites on cellular bioenergetics and cardiometabolic health
Recent research demonstrates a reciprocal relationship between gut microbiota-derived
metabolites and the host in controlling the energy homeostasis in mammals. On the one …
metabolites and the host in controlling the energy homeostasis in mammals. On the one …