Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Chronic inflammatory diseases are debilitating, affect patients' quality of life, and are a
significant financial burden on health care. Inflammation is regulated by pro-inflammatory …

This review aims to be a comprehensive, authoritative, critical, and readable review of
general interest to the medicinal chemistry community because it focuses on the …

Tumors from patients with high-grade aggressive prostate cancer (PCa) exhibit increased
expression of monoamine oxidase A (MAOA), a mitochondrial enzyme that degrades …

Monoamine oxidase (MAO) catalyzes the oxidative deamination of monoamine
neurotransmitters and dietary amines. Two pharmacological types with different substrate …

Background & Aims Monoamine oxidase A (MAOA), a catecholamine neurotransmitter
degrading enzyme, is closely associated with neurological and psychiatric disorders …

The antiandrogen enzalutamide (Enz) has improved survival in castration resistant prostate
cancer (CRPC) patients. However, most patients eventually develop Enz resistance that may …

Abstract Serotonin (5-hydroxytryptamine, 5-HT) metabolism has long been linked to
tumorigenesis and tumor progression. Numerous studies have shown the functions of 5-HT …

Monoamine oxidase (MAO) is capable of catalysing the oxidative deamination of amines
and neurotransmitters. MAO plays a pivotal role in maintaining neurotransmitters linked to …

Prostate cancer (PCa) is a major cause of mortality and morbidity in men. Available
therapies yield limited outcome. We explored anti-PCa activity in a polyphenol-rich fraction …