Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Hyperpolarized NMR Spectroscopy: d‐DNP, PHIP, and SABRE Techniques

KV Kovtunov, EV Pokochueva… - Chemistry–An Asian …, 2018 - Wiley Online Library
The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …

NMR hyperpolarization techniques for biomedicine

P Nikolaou, BM Goodson… - Chemistry–A European …, 2015 - Wiley Online Library
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques

AB Schmidt, CR Bowers, K Buckenmaier… - Analytical …, 2022 - ACS Publications
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …

Recent advances in the application of parahydrogen in catalysis and biochemistry

G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …

NMR hyperpolarization techniques of gases

DA Barskiy, AM Coffey, P Nikolaou… - … A European Journal, 2017 - Wiley Online Library
Nuclear spin polarization can be significantly increased through the process of
hyperpolarization, leading to an increase in the sensitivity of nuclear magnetic resonance …

Heterogeneous Catalysis and Parahydrogen‐Induced Polarization

EV Pokochueva, DB Burueva, OG Salnikov… - …, 2021 - Wiley Online Library
Parahydrogen‐induced polarization with heterogeneous catalysts (HET‐PHIP) has been a
subject of extensive research in the last decade since its first observation in 2007. While …

Ultra-low-cost disposable hand-held clinical-scale propane gas hyperpolarizer for pulmonary magnetic resonance imaging sensing

NM Ariyasingha, A Samoilenko, JR Birchall… - ACS …, 2023 - ACS Publications
Hyperpolarized magnetic resonance imaging (MRI) contrast agents are revolutionizing the
field of biomedical imaging. Hyperpolarized Xe-129 was recently FDA approved as an …

Silica‐Encapsulated Pt‐Sn Intermetallic Nanoparticles: A Robust Catalytic Platform for Parahydrogen‐Induced Polarization of Gases and Liquids

EW Zhao, R Maligal‐Ganesh, C Xiao… - Angewandte …, 2017 - Wiley Online Library
Recently, a facile method for the synthesis of size‐monodisperse Pt, Pt3Sn, and PtSn
intermetallic nanoparticles (iNPs) that are confined within a thermally robust mesoporous …

Toward lung ventilation imaging using hyperpolarized diethyl ether gas contrast agent

NM Ariyasingha, MRH Chowdhury… - … A European Journal, 2024 - Wiley Online Library
Hyperpolarized 129Xe gas was FDA‐approved as an inhalable contrast agent for magnetic
resonance imaging of a wide range of pulmonary diseases in December 2022. Despite the …