The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

The 5-membered oxadiazole and thiadiazole scaffolds are the most privileged and well-
known heterocycles, being a common and essential feature of a variety of natural products …

Cancer has been cursed for human beings for long time. Millions people lost their lives due
to cancer. Despite of the several anticancer drugs available, cancer cannot be cured; …

A new series of bis-benzimidazole clubbed with primary amine (3i-iii) and aromatic
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …

Two series of Benzimidazole clubbed with triazolo-thiadiazoles (5a–q, 5r, 5s and 5x–a1)
and triazolo-thiadiazines (5t–w) were synthesized with an aim to produce promising …

Scientific community is striving to understand the role of heterocycles and fused
heterocycles in drug discovery programme due to its impact on multi-drug resistance (MDR) …

In this study we have performed the in vitro anticancer activity of spiro oxindole derivatives
against MCF-7 (human Adreno carcinoma) and MDA-MB-231 (triple negative breast cancer) …

The development of anticancer compounds targeting the colchicine-binding site of tubulin,
termed colchicine-binding site inhibitors (CBSIs) is a promising research area for …

The synthesis of benzimidazole linked oxadiazole derivatives designed as potential EGFR
and erbB2 receptor inhibitors with anticancer and apoptotic activity were studied …

Recently, there has been wide interest in compounds containing the oxadiazole scaffold
because of their unique chemical structure and their broad spectrum of biological properties …