Individualizing patient treatment is a core objective of the medical field. Reaching this
objective has been elusive owing to the complex set of factors contributing to both disease …

The cardiovascular research and clinical communities are ideally positioned to address the
epidemic of noncommunicable causes of death, as well as advance our understanding of …

Patient-specific computer models have been developed representing a variety of aspects of
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics …

Human cardiac organoids (hCOs), three-dimensional (3D) cellular constructs similar to in
vivo organ, are new-generation models. To a large extent, a hCO retains the biological …

Metabolomics is a rapidly expanding field of systems biology that is gaining significant
attention in many areas of biomedical research. Also known as metabonomics, it comprises …

Autism spectrum disorder (ASD) refers to a heterogeneous group of complex
neurodevelopmental disorders characterized by social skill and communication deficits …

Endothelial dysfunction is involved in the process of acute myocardial infarction (AMI), that
is, the endothelial cell–specific molecule 1 (ESM-1; endocan) is a novel endothelial …

Ultrasound imaging has long been playing a central role in detecting abdominal aortic
aneurysms (AAAs). With a recent trend of reducing prevalence of AAAs, ultrasound …

Pharmacogenetic variants are associated with clinical outcomes during Calcium Channel
Blocker (CCB) treatment, yet whether the effects are modified by genetically predicted …

Background—Afterload reduction is a cornerstone in the management of patients with heart
failure (HF) and reduced ejection fraction. However, arterial load and the effect of HF …