A comparison of tissue dissection techniques for diagnostic, prognostic, and theragnostic analysis of human disease

EM Walsh, MK Halushka - Pathobiology, 2023 - karger.com
Histopathology has historically been the critical technique for the diagnosis and treatment of
human disease. Today, genomics, transcriptomics, and proteomics from specific cells, rather …

Maternal metabolites indicative of mental health status during pregnancy

K Laketic, S Lalonde-Bester, K Smyth, DM Slater… - Metabolites, 2022 - mdpi.com
Approximately 25% of individuals report poor mental health during their pregnancy or
postpartum period, which may impact fetal neurodevelopment, birth outcomes, and maternal …

Assessing the impact of long‐term storage on the quality and integrity of biological specimens in a reproductive biobank

Z Wang, C Zhang, X Zhang, Y Bian… - … & Translational Medicine, 2024 - Wiley Online Library
Biobanks hold a pivotal role in facilitating translational and clinical research endeavors.
However, the effects of prolonged storage on frozen blood samples analytes are not well …

Effects of freezing and rewarming methods on RNA quality of blood samples

C Zou, C Ji, Y Zhu, N Liu, S Zhang, H Peng… - Biopreservation and …, 2023 - liebertpub.com
Background: RNA extracted from human blood has been widely applied to biological,
medical, and clinical research of numerous diseases. Previous studies have demonstrated …

PUM1 and PGK1 are Favorable Housekeeping Genes over Established Biodosimetry-related Housekeeping Genes such as HPRT1, ITFG1, DPM1, MRPS5, 18S …

R Muhtadi, S Stewart, F Bunert… - Radiation …, 2024 - meridian.allenpress.com
In gene expression (GE) studies, housekeeping genes (HKGs) are required for
normalization purposes. In large-scale inter-laboratory comparison studies, significant …

Whole Blood Transcriptome Analysis in Patients with Trigeminal Neuralgia: a Prospective Clinical Study

T Liu, C Xu, J Guo, Z He, Y Zhang, Y Feng - Journal of Molecular …, 2024 - Springer
Trigeminal neuralgia (TN) brings a huge burden to patients, without long-term effective
treatment. This study aimed to explore the differentially expressed genes (DEGs) and related …

Creating an Annotated Biospecimen Resource for Liquid Biopsy Applications

SJ Skates, M Watson, D Elashoff - … Tumor Cells: Advances in Liquid Biopsy …, 2023 - Springer
The development and subsequent ready accessibility of an annotated, high-quality human
biospecimen resource is essential for the validation of liquid biopsybiomarkers and …

MALAT1 DEREPRESSES MIR-433-3P-MEDIATED RPTOR SUPPRESSION TO IMPAIR AUTOPHAGY AND DRIVE PYROPTOSIS IN ENDOTOXEMIA

K Wu, X Yu, Y Wang, X Li, Y An, Z Zhao, L Ma - Shock, 2023 - journals.lww.com
Objective Autophagy elevation in endotoxemia plays a protective role by negatively
regulating the pyroptosis of vascular endothelial cells, but the molecular mechanisms are …

Prevalence of pathogens in wild bumble bees nearby commercially reared bumble bees and an investigation of seasonal variation in distribution

S Nordgren - 2024 - diva-portal.org
As pollinators bumble bees play the crucial role of contributing to propagation of flowering
plants in favour of food production as well as biodiversity. Over the course of a few decades …

Lipid Genetics In Pregnant Women: Maneuvering the Challenges of Using Degraded Samples

K Meece - 2024 - digitalcommons.wku.edu
The results of this project will explore a novel approach to lipid metabolism in pregnant
women by exploring the relationship between maternal gene expression of genes critical for …