Therapeutic genome editing has the potential to cure diseases by directly correcting genetic
mutations in tissues and cells. Recent progress in the clustered regularly interspaced short …

The perinatal period is a sensitive time in mammalian development that can have long-
lasting consequences on offspring phenotype via maternal effects. Maternal effects have …

Stem cell transplantation is a promising method in the treatment of spinal cord injury (SCI).
Researches have shown that stem cell-derived exosomes as well as its contents such as …

Extracellular vesicles (EVs) are a heterogeneous family of extracellular structures bounded
by a phospholipid bilayer, released by all cell types in various biological fluids, such as …

Background Optic neuropathy has become a new typical syndromic multi-system disease
that leads to optic atrophy. This review discusses potential treatments and advances of …

Peripheral inflammation induced by endotoxemia or surgical stress induces
neuroinflammation thereby causing neurological symptoms ranging from sickness behavior …

This book is based on therapeutic strategies against neurodegenerative disorders (NDDs).
Currently, NDDs have become a severe burden for patients and community healthcare …

Neurodegenerative disorders are a diverse cohort of ailments marked by gradual neuronal
damage. Accumulating evidence suggests the function of exosomes in the pathogenesis of …

Brain delivery of therapeutic antibodies and biologics is restricted due to the presence of the
blood-brain barrier (BBB). However, their delivery can be improved with the use of “carrier” …

Ischemic stroke is a major cause of death and disability, demanding innovative and
accessible therapeutic strategies. Approaches presenting an optimal period for therapeutic …