Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Vascular epidermal growth factor receptor-2 (VEGFR-2), as an important tyrosine
transmembrane protein, plays an important role in regulating endothelial cell proliferation …

Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …

Knoevenagel condensation is an entrenched, prevailing, prominent arsenal following
greener principles in the generation of α, β‐unsaturated ketones/carboxylic acids by …

Five-membered heteroaromatic rings, in particular, have gained prominence in medicinal
chemistry as they offer enhanced metabolic stability, solubility and bioavailability, crucial …

Many types of cancer are associated with excessive angiogenesis. Anti-angiogenic
treatment is an effective strategy for treating solid cancers. This study aimed to demonstrate …

The vascular endothelial growth factor receptor (VEGFR) system is the key component for
controlling angiogenesis in cancer cells. Blocking vascular endothelial growth factor …

Compounds with a pyrazoline scaffold are useful as sensors for fluorescence detection of
different types of analytes. Recovery of a pyrazoline-based sensor with a view to use it …

A facile and ultrasound assisted green methodology was adopted to achieve spirooxindolo-
1, 2, 4-oxadiazoles via a [3+ 2] cycloaddition of aryl nitrile oxides and isatin Schiff bases at …

In cancer treatment, multi-target approach has paid attention to a reasonable strategy for the
potential agents. We investigated whether (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en …