Vascular mechanobiology: homeostasis, adaptation, and disease

JD Humphrey, MA Schwartz - Annual review of biomedical …, 2021 - annualreviews.org
Cells of the vascular wall are exquisitely sensitive to changes in their mechanical
environment. In healthy vessels, mechanical forces regulate signaling and gene expression …

Proliferating active matter

O Hallatschek, SS Datta, K Drescher, J Dunkel… - Nature Reviews …, 2023 - nature.com
The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

The reproduction number of COVID-19 and its correlation with public health interventions

K Linka, M Peirlinck, E Kuhl - Computational mechanics, 2020 - Springer
Throughout the past six months, no number has dominated the public media more
persistently than the reproduction number of COVID-19. This powerful but simple concept is …

Precision medicine in human heart modeling: perspectives, challenges, and opportunities

M Peirlinck, FS Costabal, J Yao, JM Guccione… - … and modeling in …, 2021 - Springer
Precision medicine is a new frontier in healthcare that uses scientific methods to customize
medical treatment to the individual genes, anatomy, physiology, and lifestyle of each person …

Multiscale modeling meets machine learning: What can we learn?

GCY Peng, M Alber, A Buganza Tepole… - … Methods in Engineering, 2021 - Springer
Abstract Machine learning is increasingly recognized as a promising technology in the
biological, biomedical, and behavioral sciences. There can be no argument that this …

Mechanochemistry of collagen

SM Siadat, JW Ruberti - Acta Biomaterialia, 2023 - Elsevier
The collagen molecular family is the result of nearly one billion years of evolution. It is a
unique family of proteins, the majority of which provide general mechanical support to …

Bio-inspired non self-similar hierarchical elastic metamaterials

M Mazzotti, A Foehr, OR Bilal, A Bergamini… - International Journal of …, 2023 - Elsevier
Hierarchy provides unique opportunities for the design of advanced materials with superior
properties that arise from architecture, rather than from constitutive material response …

Constrained mixture models of soft tissue growth and remodeling–twenty years after

JD Humphrey - Journal of Elasticity, 2021 - Springer
Soft biological tissues compromise diverse cell types and extracellular matrix constituents,
each of which can possess individual natural configurations, material properties, and rates …

Cell proliferation and migration explain pore bridging dynamics in 3D printed scaffolds of different pore size

PR Buenzli, M Lanaro, CS Wong, MP McLaughlin… - Acta Biomaterialia, 2020 - Elsevier
Tissue growth in bioscaffolds is influenced significantly by pore geometry, but how this
geometric dependence emerges from dynamic cellular processes such as cell proliferation …

Three-dimensional chiral morphodynamics of chemomechanical active shells

S Yin, B Li, XQ Feng - … of the National Academy of Sciences, 2022 - National Acad Sciences
Morphogenesis of active shells such as cells is a fundamental chemomechanical process
that often exhibits three-dimensional (3D) large deformations and chemical pattern …