Biomolecular damage induced by ionizing radiation: the direct and indirect effects of low-energy electrons on DNA

E Alizadeh, TM Orlando, L Sanche - Annual review of physical …, 2015 - annualreviews.org
Many experimental and theoretical advances have recently allowed the study of direct and
indirect effects of low-energy electrons (LEEs) on DNA damage. In an effort to explain how …

Precursors of solvated electrons in radiobiological physics and chemistry

E Alizadeh, L Sanche - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION When a high-energy charged particle interacts with a biomolecule in
living tissues or cells, about 80% of the energy absorbed ionizes the medium, whereas the …

Low energy electron-driven damage in biomolecules

L Sanche - The European Physical Journal D-Atomic, Molecular …, 2005 - Springer
The damage induced by the impact of low energy electrons (LEE) on biomolecules is
reviewed from a radiobiological perspective with emphasis on transient anion formation. The …

DNA strand breaks induced by 0–4 eV electrons: The role of shape resonances

F Martin, PD Burrow, Z Cai, P Cloutier, D Hunting… - Physical review …, 2004 - APS
Collisions of 0–4 eV electrons with thin DNA films are shown to produce single strand
breaks. The yield is sharply structured as a function of electron energy and indicates the …

Electron-induced damage of DNA and its components: Experiments and theoretical models

I Baccarelli, I Bald, FA Gianturco, E Illenberger… - Physics Reports, 2011 - Elsevier
It is now over ten years since the seminal experiments of Leon Sanche's group in
Sherbrooke have compellingly shown that subexcitation electrons interacting with DNA …

Site-specific dissociation of DNA bases by slow electrons at early stages of irradiation

H Abdoul-Carime, S Gohlke, E Illenberger - Physical review letters, 2004 - APS
At the very early time of irradiation, ballistic secondary electrons are produced as the most
abundant of the radiolytic species directly within DNA or its environment. Here, we …

Dissociative electron attachment to DNA

X Pan, P Cloutier, D Hunting, L Sanche - Physical review letters, 2003 - APS
Electron-stimulated desorption of anions from thin films of linear and supercoiled DNA is
investigated in the range 3–20 eV. Resonant structures are observed with maxima at …

Low-energy shape resonances of a nucleobase in water

GA Cooper, CJ Clarke, JRR Verlet - Journal of the American …, 2022 - ACS Publications
When high-energy radiation passes through aqueous material, low-energy electrons are
produced which cause DNA damage. Electronic states of anionic nucleobases have been …

Inelastic electron interaction (attachment/ionization) with deoxyribose

S Ptasińska, S Denifl, P Scheier… - The Journal of chemical …, 2004 - pubs.aip.org
We have investigated experimentally the formation of anions and cations of deoxyribose
sugar (C 5 H 10 O 4) via inelastic electron interaction (attachment/ionization) using a …

Electron attachment to the gas-phase DNA bases cytosine and thymine

S Denifl, S Ptasińska, M Probst, J Hrušák… - The Journal of …, 2004 - ACS Publications
We present a detailed study on dissociative electron attachment (DEA) to isolated gas-
phase cytosine (C) and thymine (T). The experimental setup used for these measurements is …