Rationale Exposure to social defeat (SD) induces a depressive phenotype, increased
ethanol seeking and consumption, accompanied by activation of the neuroinflammatory …

Despite the prevalence and public health impact of substance use disorders (SUDs),
effective long‐term treatments remain elusive. Aerobic exercise is a promising …

Prior physical activity reduces the risk of future stress-related mental health disorders
including depression, anxiety, and post-traumatic stress disorder. Rodents allowed to …

The present paper evaluates the effect of physical activity on the increase of the conditioned
rewarding effects of cocaine induced by intermittent social stress and on the …

Attention-deficit hyperactivity disorder (ADHD) affects around 5% of children and adults
worldwide (Polanczyk et al., 2015; Simon et al., 2009) and is characterised by inattention …

Rationale In previous animal model studies, it was shown that drug sensitization is
dependent upon physical environmental conditions. However, the effects of social housing …

Exercise is known to promote efficient function of stress circuitry. The developing brain is
malleable and thus exercise during adolescence could potentially exert lasting beneficial …

While animal research has consistently reported preventive effects of exercise against drug
abuse vulnerability, little is known about the influence of the developmental stage during …

Wheel-running in rodents can mitigate addiction-related effects of drugs of abuse like
cocaine. However, conditioned place preference (CPP) experiments have reported …

The timing of voluntary exercise relative to drug conditioning is important to its
“neuroprotective” effects, though it is unclear whether the voluntary exercise needs to occur …