Non‐invasive prenatal testing (NIPT) for aneuploidy using cell‐free DNA in maternal plasma
is revolutionizing prenatal screening and diagnosis. We review NIPT in the context of …

Objectives The implementation of chromosomal microarray analysis (CMA) in prenatal
testing for all patients has not achieved a consensus. Technical alternatives such as …

Quantitative fluorescent polymerase chain reaction has been in diagnostic use in the UK for
over 10 years and has proved to be a cost‐effective, robust and accurate rapid prenatal test …

Background Emerging evidence supports an association between vaginal microbiota
composition and risk of miscarriage; however, the underlying mechanisms are poorly …

Abstract Although 22q11. 2 deletion syndrome (22q11. 2DS) is the most recurrent human
microdeletion syndrome associated with a highly variable phenotype, little is known about …

Objective We previously reported on the validation of Prenatal BACs‐on‐BeadsTM on
retrospectively selected and prospective prenatal samples. This bead‐based multiplex …

Genomic integrity of human pluripotent stem cell (hPSC) lines requires routine monitoring.
We report here that novel karyotyping assay, utilizing bead-bound bacterial artificial …

Objective To evaluate the diagnostic performance of the BAC s‐on‐Beads™(BoBs™) assay
for prenatal detection of chromosomal abnormalities. Design Retrospective study. Setting …

Objective To understand the prenatal referral patterns from the United States, Canada, and
Israel for two whole‐genome microarray platforms, each with a different resolution. Method …

Objective To present the results of 10 years of quantitative fluorescence PCR (QF‐PCR)
analysis of prenatal samples for the rapid diagnosis of the common aneuploidies. This …