Physical bioenergetics: Energy fluxes, budgets, and constraints in cells

X Yang, M Heinemann, J Howard… - Proceedings of the …, 2021 - National Acad Sciences
Cells are the basic units of all living matter which harness the flow of energy to drive the
processes of life. While the biochemical networks involved in energy transduction are well …

Nonequilibrium thermodynamics in biochemical systems and its application

D Zhang, Q Ouyang - Entropy, 2021 - mdpi.com
Living systems are open systems, where the laws of nonequilibrium thermodynamics play
the important role. Therefore, studying living systems from a nonequilibrium thermodynamic …

Flow of Energy and Information in Molecular Machines

MP Leighton, DA Sivak - arXiv preprint arXiv:2406.10355, 2024 - arxiv.org
Molecular machines transduce free energy between different forms throughout all living
organisms. While truly machines in their own right, unlike their macroscopic counterparts …

Carnot, Stirling, and Ericsson stochastic heat engines: Efficiency at maximum power

O Contreras-Vergara, N Sánchez-Salas… - Physical Review E, 2023 - APS
This work uses the low-dissipation strategy to obtain efficiency at maximum power from a
stochastic heat engine performing Carnot-, Stirling-and Ericsson-like cycles at finite time …

Theoretical efficiency limits and speed-efficiency trade-off in myosin motors

A Vilfan, A Šarlah - PLOS Computational Biology, 2023 - journals.plos.org
Muscle myosin is a non-processive molecular motor that generates mechanical work when
cooperating in large ensembles. During its cyle, each individual motor keeps attaching and …

An empirical energy landscape reveals mechanism of proteasome in polypeptide translocation

R Fang, J Hon, M Zhou, Y Lu - Elife, 2022 - elifesciences.org
The ring-like ATPase complexes in the AAA+ family perform diverse cellular functions that
require coordination between the conformational transitions of their individual ATPase …

Modeling bacterial flagellar motor with new structure information: Rotational dynamics of two interacting protein nano-rings

Y Cao, T Li, Y Tu - Frontiers in Microbiology, 2022 - frontiersin.org
In this article, we develop a mathematical model for the rotary bacterial flagellar motor (BFM)
based on the recently discovered structure of the stator complex (MotA5MotB2). The …

Stochastic fluctuations in the rotation of the bacterial flagellar motor

G Yue, R Zhang, J Yuan - Chinese Physics B, 2023 - iopscience.iop.org
The bacterial flagellar motor is a nanometer-sized rotary motor that generates the torque to
drive the rotation of the flagellar filament. The output torque is an important property of the …

A forced thermal ratchet in a memory heat bath

O Contreras-Vergara, N Sánchez-Salas… - arXiv preprint arXiv …, 2022 - arxiv.org
The present work studies a non-Markovian forced thermal ratchet model on an asymmetric
periodic potential. The Brownian dynamics is described by a generalized Langevin equation …

The Systems Biology of the Protein Quality Control

R Fang - 2023 - search.proquest.com
The 26S proteasome, an ATP-dependent protease, is the main powerhouse for protein
degradation in all eukaryotic cells. Proteostasis is maintained by the ubiquitin-proteasome …