In contrast to almost all other brain tumors, diffuse gliomas infiltrate extensively in the
neuropil. This growth pattern is a major factor in therapeutic failure. Diffuse infiltrative glioma …

Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021
WHO CNS5 classification has further stressed the importance of molecular signatures in …

Localized proton magnetic resonance spectroscopy (MRS) of the human brain, first reported
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …

Purpose To quantitatively compare the potential of various diffusion parameters obtained
from monoexponential, biexponential, and stretched exponential diffusion-weighted imaging …

Magnetic resonance imaging is integral to the care of patients with high-grade gliomas.
Anatomic detail can be acquired with conventional structural imaging, but newer …

Background The standard of care for glioblastoma (GBM) is maximal safe resection followed
by radiation therapy with chemotherapy. Currently, contrast-enhanced MRI is used to define …

Introduction Diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI) and MR
spectroscopy (MRS) provide useful data for tumor evaluation. To assess the contribution of …

The revolution in cancer genomics has uncovered a variety of clinically relevant mutations in
primary brain tumours, creating an urgent need to develop non-invasive imaging biomarkers …

To assess the capability of perfusion MRI to differentiate between necrosis and tumor
recurrence in patients showing radiological progression of cerebral metastases treated with …

Introduction To perform a meta-analysis of advanced magnetic resonance imaging (MRI)
metrics, including relative cerebral blood volume (rCBV), normalized apparent diffusion …