Biological functions of RBP4 and its relevance for human diseases
JS Steinhoff, A Lass, M Schupp - Frontiers in Physiology, 2021 - frontiersin.org
Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …
Current state of evidence: influence of nutritional and nutrigenetic factors on immunity in the COVID-19 pandemic framework
The pandemic caused by the new coronavirus has caused shock waves in many countries,
producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms …
producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms …
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
Retinoids are micronutrients that are stored as retinyl esters in the retina and hepatic stellate
cells (HSCs). HSCs are key players in fibrogenesis in chronic liver diseases. The enzyme …
cells (HSCs). HSCs are key players in fibrogenesis in chronic liver diseases. The enzyme …
Diet-derived circulating antioxidants and risk of coronary heart disease: a Mendelian randomization study
Background Previously, observational studies have identified associations between higher
levels of dietary-derived antioxidants and lower risk of coronary heart disease (CHD) …
levels of dietary-derived antioxidants and lower risk of coronary heart disease (CHD) …
An atlas of associations between 14 micronutrients and 22 cancer outcomes: Mendelian randomization analyses
Background Micronutrients, namely vitamins and minerals, are associated with cancer
outcomes; however, their reported effects have been inconsistent across studies. We aimed …
outcomes; however, their reported effects have been inconsistent across studies. We aimed …
Circulating levels of micronutrients and risk of infections: a Mendelian randomization study
Background Micronutrients play an essential role at every stage of the immune response,
and deficiencies can therefore lead to increased susceptibility to infections. Previous …
and deficiencies can therefore lead to increased susceptibility to infections. Previous …
Antioxidants, minerals and vitamins in relation to Crohn's disease and ulcerative colitis: a Mendelian randomization study
Background Evidence for antioxidants, minerals and vitamins in relation to the risk of
Crohn's disease (CD) and ulcerative colitis (UC) is limited and inconsistent. This mendelian …
Crohn's disease (CD) and ulcerative colitis (UC) is limited and inconsistent. This mendelian …
[HTML][HTML] Retinol-binding protein 4 in obesity and metabolic dysfunctions
PAN Nankam, M Blüher - Molecular and Cellular Endocrinology, 2021 - Elsevier
Excessive increased adipose tissue mass in obesity is associated with numerous co-morbid
disorders including increased risk of type 2 diabetes, fatty liver disease, hypertension …
disorders including increased risk of type 2 diabetes, fatty liver disease, hypertension …
An updated comprehensive review on vitamin A and carotenoids in breast cancer: mechanisms, genetics, assessment, current evidence, and future clinical …
JA Kim, JH Jang, SY Lee - Nutrients, 2021 - mdpi.com
Vitamin A and carotenoids are fat-soluble micronutrients that play important role as powerful
antioxidants modulating oxidative stress and cancer development. Breast cancer is the most …
antioxidants modulating oxidative stress and cancer development. Breast cancer is the most …
[HTML][HTML] CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with …
P Borel, G Lietz, A Goncalves, FS de Edelenyi… - The Journal of …, 2013 - Elsevier
Scavenger receptor class B type I (SR-BI) and cluster determinant 36 (CD36) have been
involved in cellular uptake of some provitamin A carotenoids. However, data are incomplete …
involved in cellular uptake of some provitamin A carotenoids. However, data are incomplete …