Biological functions of RBP4 and its relevance for human diseases

JS Steinhoff, A Lass, M Schupp - Frontiers in Physiology, 2021 - frontiersin.org
Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …

Current state of evidence: influence of nutritional and nutrigenetic factors on immunity in the COVID-19 pandemic framework

S Galmés, F Serra, A Palou - Nutrients, 2020 - mdpi.com
The pandemic caused by the new coronavirus has caused shock waves in many countries,
producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms …

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

C Pirazzi, L Valenti, BM Motta, P Pingitore… - Human molecular …, 2014 - academic.oup.com
Retinoids are micronutrients that are stored as retinyl esters in the retina and hepatic stellate
cells (HSCs). HSCs are key players in fibrogenesis in chronic liver diseases. The enzyme …

Diet-derived circulating antioxidants and risk of coronary heart disease: a Mendelian randomization study

J Luo, S le Cessie, D van Heemst… - Journal of the American …, 2021 - jacc.org
Background Previously, observational studies have identified associations between higher
levels of dietary-derived antioxidants and lower risk of coronary heart disease (CHD) …

An atlas of associations between 14 micronutrients and 22 cancer outcomes: Mendelian randomization analyses

JY Kim, M Song, MS Kim, P Natarajan, R Do, W Myung… - BMC medicine, 2023 - Springer
Background Micronutrients, namely vitamins and minerals, are associated with cancer
outcomes; however, their reported effects have been inconsistent across studies. We aimed …

Circulating levels of micronutrients and risk of infections: a Mendelian randomization study

HM Flatby, A Ravi, JK Damås, E Solligård, T Rogne - BMC medicine, 2023 - Springer
Background Micronutrients play an essential role at every stage of the immune response,
and deficiencies can therefore lead to increased susceptibility to infections. Previous …

Antioxidants, minerals and vitamins in relation to Crohn's disease and ulcerative colitis: a Mendelian randomization study

J Chen, X Ruan, S Yuan, M Deng… - Alimentary …, 2023 - Wiley Online Library
Background Evidence for antioxidants, minerals and vitamins in relation to the risk of
Crohn's disease (CD) and ulcerative colitis (UC) is limited and inconsistent. This mendelian …

[HTML][HTML] Retinol-binding protein 4 in obesity and metabolic dysfunctions

PAN Nankam, M Blüher - Molecular and Cellular Endocrinology, 2021 - Elsevier
Excessive increased adipose tissue mass in obesity is associated with numerous co-morbid
disorders including increased risk of type 2 diabetes, fatty liver disease, hypertension …

An updated comprehensive review on vitamin A and carotenoids in breast cancer: mechanisms, genetics, assessment, current evidence, and future clinical …

JA Kim, JH Jang, SY Lee - Nutrients, 2021 - mdpi.com
Vitamin A and carotenoids are fat-soluble micronutrients that play important role as powerful
antioxidants modulating oxidative stress and cancer development. Breast cancer is the most …

[HTML][HTML] CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with …

P Borel, G Lietz, A Goncalves, FS de Edelenyi… - The Journal of …, 2013 - Elsevier
Scavenger receptor class B type I (SR-BI) and cluster determinant 36 (CD36) have been
involved in cellular uptake of some provitamin A carotenoids. However, data are incomplete …