Acute-on-chronic liver failure: terminology, mechanisms and management

SK Sarin, A Choudhury - Nature Reviews Gastroenterology & …, 2016 - nature.com
Acute-on-chronic liver failure (ACLF) is a distinct clinical entity and differs from acute liver
failure and decompensated cirrhosis in timing, presence of acute precipitant, course of …

Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis

JCQ Velez, G Therapondos, LA Juncos - Nature Reviews Nephrology, 2020 - nature.com
The occurrence of acute kidney injury (AKI) in patients with end-stage liver disease
constitutes one of the most challenging clinical scenarios in in-hospital and critical care …

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

SK Sarin, A Choudhury, MK Sharma, R Maiwall… - Hepatology …, 2019 - Springer
The first consensus report of the working party of the Asian Pacific Association for the Study
of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published …

Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis

R Moreau, R Jalan, P Gines, M Pavesi, P Angeli… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Patients with cirrhosis hospitalized for an acute decompensation
(AD) and organ failure are at risk for imminent death and considered to have acute-on …

Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014

SK Sarin, CK Kedarisetty, Z Abbas… - Hepatology …, 2014 - Springer
The first consensus report of the working party of the Asian Pacific Association for the Study
of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published …

Allogeneic bone marrow–derived mesenchymal stromal cells for hepatitis B virus–related acute‐on‐chronic liver failure: a randomized controlled trial

B Lin, J Chen, W Qiu, K Wang, D Xie, X Chen… - …, 2017 - Wiley Online Library
Mortality from hepatitis B virus (HBV)–related acute‐on‐chronic liver failure (ACLF) is high
due to limited treatment options. Preclinical and clinical investigations have proved that …

Terlipressin is superior to noradrenaline in the management of acute kidney injury in acute on chronic liver failure

V Arora, R Maiwall, V Rajan, A Jindal, SM Shasthry… - Hepatology, 2020 - journals.lww.com
Hepatorenal syndrome (HRS) carries a high short‐term mortality in patients with cirrhosis
and acute on chronic liver failure (ACLF). Terlipressin and noradrenaline are routinely used …

Liver failure determines the outcome in patients of acute-on-chronic liver failure (ACLF): comparison of APASL ACLF research consortium (AARC) and CLIF-SOFA …

A Choudhury, A Jindal, R Maiwall, MK Sharma… - Hepatology …, 2017 - Springer
Background and aims Acute-on-chronic liver failure (ACLF) is a progressive disease
associated with rapid clinical worsening and high mortality. Early prediction of mortality and …

[PDF][PDF] Acute‐on‐chronic liver failure: excellent outcomes after liver transplantation but high mortality on the wait list

A Finkenstedt, K Nachbaur, H Zoller… - Liver …, 2013 - Wiley Online Library
Acute‐on‐chronic liver failure (ACLF) is characterized by high short‐term mortality. Liver
transplantation (LT) is a potential therapy for patients who do not improve with supportive …

A systematic review on prognostic indicators of acute on chronic liver failure and their predictive value for mortality

KA Wlodzimirow, S Eslami, A Abu‐Hanna… - Liver …, 2013 - Wiley Online Library
Background An early and proper diagnosis of acute on chronic liver failure (ACLF), together
with the identification of indicators associated with disease severity is critical for outcome …