Combined oral 5-azacytidine and romidepsin are highly effective in patients with PTCL: a multicenter phase 2 study
L Falchi, H Ma, S Klein, JK Lue… - Blood, The Journal …, 2021 - ashpublications.org
Peripheral T-cell lymphomas (PTCLs) are uniquely vulnerable to epigenetic modifiers. We
demonstrated in vitro synergism between histone deacetylase inhibitors and DNA …
demonstrated in vitro synergism between histone deacetylase inhibitors and DNA …
[HTML][HTML] Immune check point inhibitors in primary cutaneous T-cell lymphomas: biologic rationale, clinical results and future perspectives
G Roccuzzo, S Giordano, P Fava, A Pileri… - Frontiers in …, 2021 - frontiersin.org
Primary cutaneous T-cell lymphomas (PCTCL) are the most common types of cutaneous
lymphomas, with Mycosis fungoides as the most frequent subtype. Besides early stages …
lymphomas, with Mycosis fungoides as the most frequent subtype. Besides early stages …
Enhancing antitumor immunity through checkpoint blockade as a therapeutic strategy in T-cell lymphomas
A Neuwelt, T Al-Juhaishi, E Davila… - Blood Advances, 2020 - ashpublications.org
The majority of historical therapies for managing T-cell lymphomas (TCLs) have consisted of
T-cell–depleting strategies. Unfortunately, these forms of therapies can hamper the ability to …
T-cell–depleting strategies. Unfortunately, these forms of therapies can hamper the ability to …
Clinical Experience with Epigenetic Drugs in Lymphoid Malignancies
E Marchi, I Pal, JS Manavalan - Precision Cancer Therapies …, 2023 - Wiley Online Library
This chapter is focused on the role of epigenetic agents in the treatment of lymphoid
malignancies. The study of epigenetics is a complex topic that has significantly evolved over …
malignancies. The study of epigenetics is a complex topic that has significantly evolved over …
Innovative Chemotherapy‐free Approaches for the Treatment of Peripheral T‐Cell Lymphoma
E Marchi, A Sawas, H Ma, L Scotto… - The Peripheral T‐Cell …, 2021 - Wiley Online Library
The discovery of new therapeutic agents followed by the subsequent development of novel
drug–drug combinations has been one of the most exciting areas in cancer medicine. This …
drug–drug combinations has been one of the most exciting areas in cancer medicine. This …