Oxidative stress has a critical role in the pathophysiology of several kidney diseases, and
many complications of these diseases are mediated by oxidative stress, oxidative stress …

Gout is well known as an inflammatory rheumatic disease presenting with arthritis and
abnormal metabolism of uric acid. The recognition of diet-induced systemic metabolic …

The concept of reversing chronic kidney disease (CKD) has been intensively researched
over the past decade. Indeed, as the prevalence of end-stage renal disease is constantly on …

Objective To assess the effect of vitamin C supplementation on serum uric acid (SUA) by
pooling the findings from published randomized controlled trials (RCTs). Methods A total of …

Hypertension is a multifactorial disease involving complex interactions between genetic and
environmental factors. Development of experimental models of hypertension allowed …

Background—Endothelial progenitor cells (EPCs) promote neovascularization and
endothelial repair. Renal artery stenosis (RAS) may impair renal function by inducing …

The superoxide generating enzyme NADPH oxidase has received much attention as a
major cause of oxidative stress underlying vascular disease. However, there is increasing …

Atherosclerosis represents one of the major causes of premature death in the United States
today, and it is frequently associated with, exacerbates, and is aggravated by chronic kidney …

An intact microcirculation is vital for diffusion of oxygen and nutrients and for removal of
toxins of every organ and system in the human body. The functional and/or anatomical loss …

Objective We examined associations between vitamin C intake and serum uric acid in men
in a population-based study. Methods We included 1387 men without hypertension and with …