In recent years, epigenetic modifications have been widely researched. As humans age,
environmental and genetic factors may drive inflammation and immune responses by …

Abstract Sodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used to treat
diabetes mellitus. Abundant evidence has shown that SGLT2 inhibitors can reduce …

Background & aims Excessive inflammatory responses and oxidative stress are considered
the main characteristics of inflammatory bowel disease (IBD). Endogenous hydrogen sulfide …

Background Ulcerative colitis (UC) is a chronic mucosal inflammation of the large intestine
that mostly affects the rectum and colon. The absence of safe and effective therapeutic …

Ulcerative Colitis (UC) is a chronic idiopathic inflammatory bowel disease in which the
colon's lining becomes inflamed. Exploring herbal remedies that can recover mucosal …

Psoriasis is a life-long immune-mediated dermatosis with thickened, reddish, and flaky skin
patches. Canagliflozin is a gliflozin antidiabetic with non-classical remarkable antioxidative …

Rebamipide is a quinolone derivative that has been commonly used for the treatment of
gastric and duodenal ulcers. However, the molecular mechanisms of rebamipide against …

Inflammation plays an essential role and is a common feature in the pathogenesis of many
chronic diseases. The exact mechanisms through which sodium-glucose cotransporter-2 …

Intestinal barrier injury and hyperglycemia are common in patients with sepsis. Bacteria
translocation and systemic inflammatory response caused by intestinal barrier injury play a …

Inflammatory bowel disease (IBD) is a chronic life‐limiting disease of gastrointestinal tract
characterized by widespread enteric inflammation. IBD is a multifactorial disease, and …