Leptin and obesity: role and clinical implication

M Obradovic, E Sudar-Milovanovic, S Soskic… - Frontiers in …, 2021 - frontiersin.org
The peptide hormone leptin regulates food intake, body mass, and reproductive function and
plays a role in fetal growth, proinflammatory immune responses, angiogenesis and lipolysis …

Iron deficiency anaemia

A Lopez, P Cacoub, IC Macdougall, L Peyrin-Biroulet - The Lancet, 2016 - thelancet.com
Anaemia affects roughly a third of the world's population; half the cases are due to iron
deficiency. It is a major and global public health problem that affects maternal and child …

[图书][B] WHO guideline on use of ferritin concentrations to assess iron status in populations

World Health Organization - 2020 - books.google.com
This guideline provides global, evidence-informed recommendations on the use of
indicators for assessing a population's iron status and application of the use of ferritin …

British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults

J Snook, N Bhala, ILP Beales, D Cannings, C Kightley… - Gut, 2021 - gut.bmj.com
Iron deficiency anaemia (IDA) is a major cause of morbidity and burden of disease
worldwide. It can generally be diagnosed by blood testing and remedied by iron …

Criteria for iron deficiency in patients with heart failure

G Masini, FJ Graham, P Pellicori, JGF Cleland… - Journal of the American …, 2022 - jacc.org
Background Guidelines on heart failure (HF) define iron deficiency (ID) as a serum ferritin<
100 ng/mL or, when 100-299 ng/mL, a transferrin saturation (TSAT)< 20%. Inflammation …

Chemistry and biology of ferritin

M Plays, S Müller, R Rodriguez - Metallomics, 2021 - academic.oup.com
Iron is an essential element required by cells and has been described as a key player in
ferroptosis. Ferritin operates as a fundamental iron storage protein in cells forming …

[HTML][HTML] Guidelines on the diagnosis and treatment of iron deficiency across indications: a systematic review

L Peyrin-Biroulet, N Williet, P Cacoub - The American journal of clinical …, 2015 - Elsevier
Background: Guidelines on the diagnosis and treatment of iron deficiency (ID) vary widely
across indications. Objective: We reviewed all available guidelines on the management of …

Iron deficiency anemia

TG DeLoughery - Medical Clinics, 2017 - medical.theclinics.com
Iron deficiency anemia is the most common and most treatable of all anemias. There is an
evolving understanding that iron deficiency can lead to symptoms independent of anemia …

[HTML][HTML] Laboratory methodologies for indicators of iron status: strengths, limitations, and analytical challenges

CM Pfeiffer, AC Looker - The American journal of clinical nutrition, 2017 - Elsevier
Biochemical assessment of iron status relies on serum-based indicators, such as serum
ferritin (SF), transferrin saturation, and soluble transferrin receptor (sTfR), as well as …

Hyperferritinemia—a clinical overview

M Sandnes, RJ Ulvik, M Vorland… - Journal of Clinical …, 2021 - mdpi.com
Ferritin is one of the most frequently requested laboratory tests in primary and secondary
care, and levels often deviate from reference ranges. Serving as an indirect marker for total …