Advanced nanomaterials as sample technique for bio-analysis

N Sun, H Yu, H Wu, X Shen, C Deng - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

Adsorptive remediation of environmental pollutants using magnetic hybrid materials as platform adsorbents

N Ali, MDMH Riead, M Bilal, Y Yang, A Khan, F Ali… - Chemosphere, 2021 - Elsevier
Effective separation and remediation of environmentally hazardous pollutants are burning
areas of research because of a constant increase in environmental pollution problems. An …

Electrochemical cardiac troponin I immunosensor based on nitrogen and boron-doped graphene quantum dots electrode platform and Ce-doped SnO2/SnS2 signal …

O Karaman, N Özcan, C Karaman, BB Yola… - Materials Today …, 2022 - Elsevier
The detection of acute myocardial infarction directly depends on the concentration of the
cardiac troponin I (CTnI) in human blood plasma. In this study, the sensitive, selective, and …

Application of magnetic solid phase extraction in separation and enrichment of glycoproteins and glycopeptides

H Qi, L Jiang, Q Jia - Chinese Chemical Letters, 2021 - Elsevier
The analysis of endogenous glycoproteins and glycopeptides in human body fluids is of
great importance for screening and discovering disease biomarkers with clinical …

Construction of magnetic covalent organic frameworks with inherent hydrophilicity for efficiently enriching endogenous glycopeptides in human saliva

Y Wu, N Sun, C Deng - ACS applied materials & interfaces, 2020 - ACS Publications
In this work, a magnetic covalent organic framework (COF) with inherent hydrophilicity
(denoted mCTpBD) was synthesized through interface deposition of a hydrophilic COF shell …

Advances in hydrophilic nanomaterials for glycoproteomics

N Sun, H Wu, H Chen, X Shen, C Deng - Chemical Communications, 2019 - pubs.rsc.org
Owing to the formidable challenge posed by microheterogeneities in glycosylation sites,
macroheterogeneity of the modification number of glycans, and low abundance and …

Nanomaterials in proteomics

N Sun, H Wu, X Shen, C Deng - Advanced Functional Materials, 2019 - Wiley Online Library
For a deep understanding of the human proteome, the first crucial step is always the
effective separation of targeted proteins/peptides from complex samples. In mass …

Enrichment driven glycoproteomics: New materials, new methods, and beyond

Y Xiong, M Li, Y Liu, X Liang, G Qing - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Glycoproteomics is a rapidly growing field that aims to identify and characterize protein
glycosylation events at a system level. However, the analysis of protein glycosylation in …

Boronate affinity imprinted organo/hydro copolymers fabricated from Pickering emulsions reactor for specific recognition of Luteolin

X Zhang, Z Hu, S Liu, N Tang, H Ou, J Pan - Separation and Purification …, 2023 - Elsevier
To date, the flexiable organo/hydro copolymer materials have made of interest for
separation, but the utilize of Pickering emulsion from such macroporous monoliths is …

Effective enrichment strategy using boronic acid-functionalized mesoporous graphene–silica composites for intact N-and O-linked glycopeptide analysis in human …

S Kong, Q Zhang, L Yang, Y Huang, M Liu… - Analytical …, 2021 - ACS Publications
The heterogeneity and low abundance of protein glycosylation present challenging barriers
to the analysis of intact glycopeptides, which is key to comprehensively understanding the …