Iron deficiency is one of the leading contributors to the global burden of disease, and
particularly affects children, premenopausal women, and people in low-income and middle …

Background: Social changes in the 20th century resulted in substantial reductions in the
prevalence of breastfeeding in many countries but especially in those with high and …

Our goal is to present recent progress in understanding the biological mechanisms
underlying anemia from a public health perspective. We describe important advances in …

Background How specific nutrients influence adaptive immunity is of broad interest. Iron
deficiency is the most common micronutrient deficiency worldwide and imparts a significant …

Iron is indispensable for human life. However, it is also potentially toxic, since it catalyzes the
formation of harmful oxidative radicals in unbound form and may facilitate pathogen growth …

Early childhood is characterised by high physiological iron demand to support processes
including blood volume expansion, brain development and tissue growth. Iron is also …

Malaria and iron deficiency are major global health problems with extensive epidemiological
overlap. Iron deficiency-induced anaemia can protect the host from malaria by limiting …

Background In adults, oral iron doses increase plasma hepcidin (PHep) for 24 h, but not for
48 h, and there is a circadian increase in PHep over the day. Because high PHep decreases …

Iron deficiency is the most prevalent human micronutrient deficiency, disrupting the
physiological development of millions of infants and children. Oral iron supplementation is …

Iron deficiency presents a major public health concern in many malaria-endemic regions,
and both conditions affect young children most severely. Daily iron supplementation is the …