[HTML][HTML] Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance

CMN Croagh, PV Desmond, SJ Bell - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Abstract The Hepatitis B Virus (HBV) has a worldwide distribution and is endemic in many
populations. It is constantly evolving and 10 genotypic strains have been identified with …

Gender disparity in chronic hepatitis B: mechanisms of sex hormones

SH Wang, PJ Chen, SH Yeh - Journal of gastroenterology and …, 2015 - Wiley Online Library
Hepatitis B virus (HBV) is a common human pathogen transmitted worldwide, and its chronic
infection is a well‐known risk factor for hepatocellular carcinoma (HCC). The sex disparity of …

[HTML][HTML] Update on hepatitis B and C virus diagnosis

LM Villar, HM Cruz, JR Barbosa, CS Bezerra… - World journal of …, 2015 - ncbi.nlm.nih.gov
Viral hepatitis B and C virus (HBV and HCV) are responsible for the most of chronic liver
disease worldwide and are transmitted by parenteral route, sexual and vertical transmission …

Predicting mammalian species at risk of being infected by SARS-CoV-2 from an ACE2 perspective

Y Wei, P Aris, H Farookhi, X Xia - Scientific Reports, 2021 - nature.com
SARS-CoV-2 can transmit efficiently in humans, but it is less clear which other mammals are
at risk of being infected. SARS-CoV-2 encodes a Spike (S) protein that binds to human …

The potential and challenges of CRISPR-Cas in eradication of hepatitis B virus covalently closed circular DNA

HC Yang, PJ Chen - Virus research, 2018 - Elsevier
Current antiviral therapy fails to cure chronic hepatitis B virus (HBV) infection, primarily
because of the persistence of covalently closed circular DNA (cccDNA). Although nucleos (t) …

Accurate assembly of minority viral haplotypes from next-generation sequencing through efficient noise reduction

S Knyazev, V Tsyvina, A Shankar, A Melnyk… - Nucleic acids …, 2021 - academic.oup.com
Rapidly evolving RNA viruses continuously produce minority haplotypes that can become
dominant if they are drug-resistant or can better evade the immune system. Therefore, early …

Coronavirus genomes carry the signatures of their habitats

Y Wei, JR Silke, P Aris, X Xia - PLoS One, 2020 - journals.plos.org
Coronaviruses such as SARS-CoV-2 regularly infect host tissues that express antiviral
proteins (AVPs) in abundance. Understanding how they evolve to adapt or evade host …

Single-molecule sequencing reveals complex genome variation of hepatitis B virus during 15 years of chronic infection following liver transplantation

BD Betz-Stablein, A Töpfer, M Littlejohn, L Yuen… - Journal of …, 2016 - Am Soc Microbiol
Chronic hepatitis B (CHB) is prevalent worldwide. The infectious agent, hepatitis B virus
(HBV), replicates via an RNA intermediate and is error prone, leading to the rapid …

Hepatocellular carcinoma‐associated single‐nucleotide variants and deletions identified by the use of genome‐wide high‐throughput analysis of hepatitis B virus

WC Liu, IC Wu, YC Lee, CP Lin… - The Journal of …, 2017 - Wiley Online Library
This study investigated hepatitis B virus (HBV) single‐nucleotide variants (SNVs) and
deletion mutations linked with hepatocellular carcinoma (HCC). Ninety‐three HCC patients …

[PDF][PDF] Hepatitis B vaccination efficacy in Iranian healthcare workers: A meta-analysis study.

M Azami, MR Hafezi Ahmadi… - Hepatitis …, 2017 - repository.brieflands.com
Context: Despite various studies, there is no overall estimation about the efficacy of Hepatitis
B virus (HBV) vaccine among healthcare workers (including healthcare personnel and …