Endogenous opiates and behavior: 2005

RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

[HTML][HTML] Mitochondrial photobiomodulation as a neurotherapeutic strategy for epilepsy

FS Cardoso, F Gonzalez-Lima, NC Coimbra - Frontiers in Neurology, 2022 - frontiersin.org
Discovering that photobiomodulation (PBM) is neuroprotective and has augmentation effects
on human neurocognitive functions has been groundbreaking (1). Transcranial PBM with …

[HTML][HTML] GABAergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal …

M Mendonça-dos-Santos, TCT Gonçalves… - Scientific Reports, 2024 - nature.com
We investigated the participation of the nucleus of the tractus solitarius (NTS) in tonic‒clonic
seizures and postictal antinociception control mediated by NMDA receptors, the role of NTS …

Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited …

GCD Eichenberger, SJ Ribeiro, MY Osaki… - …, 2002 - Elsevier
The effects of central administration of opioid antagonists on the aversive responses elicited
by electrical (at the freezing and escape thresholds) or chemical stimulation (crossings …

Nitric oxide-mediated defensive and antinociceptive responses organised at the anterior hypothalamus of mice are modulated by glutamatergic inputs from area 24b …

LL Falconi-Sobrinho… - Journal of …, 2021 - journals.sagepub.com
Background: Previous studies suggested that Cg1 area of the cingulate cortex of rats
controls glutamate-mediated fear-induced defensive behaviour and antinociception …

Intrinsic neural circuits between dorsal midbrain neurons that control fear-induced responses and seizure activity and nuclei of the pain inhibitory system elaborating …

RL Freitas, CMR Ferreira, SJ Ribeiro, AD Carvalho… - Experimental …, 2005 - Elsevier
The blockade of GABA-mediated Cl− influx with pentylenetetrazol (PTZ) was used in the
present work to induce seizures in Rattus norvegicus. The aim of this work was to study the …

The role of dorsomedial and ventrolateral columns of the periaqueductal gray matter and in situ 5‐HT2A and 5‐HT2C serotonergic receptors in post‐ictal …

RL de Freitas, RC de Oliveira, R de Oliveira… - Synapse, 2014 - Wiley Online Library
The periaqueductal gray matter (PAG) consists in a brainstem structure rich in 5‐
hydroxytryptamine (5‐HT) inputs related to the modulation of pain. The involvement of each …

[HTML][HTML] Enhanced sensitivity of laforin-and malin-deficient mice to the convulsant agent pentylenetetrazole

AM García-Cabrero, G Sánchez-Elexpuru… - Frontiers in …, 2014 - frontiersin.org
Lafora disease is a rare form of inherited progressive myoclonus epilepsy caused by
mutations in the EPM2A gene encoding laforin, or in the EPM2B gene, which encodes …

5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus

RL Freitas, CM dos Reis Ferreira, MAC Urbina… - Experimental …, 2009 - Elsevier
Pharmacological studies have been focused on the involvement of different neural pathways
in the organization of antinociception that follows tonic-clonic seizures, including 5 …

Serotonergic neurotransmission in the dorsal raphe nucleus recruits in situ 5-HT2A/2C receptors to modulate the post-ictal antinociception

RL Freitas, GS Bassi, AM de Oliveira… - Experimental neurology, 2008 - Elsevier
The post-ictal immobility syndrome is followed by a significant increase in the nociceptive
thresholds in animals and humans. The aim of this study was to assess the involvement of …