2021 update on diffuse large B cell lymphoma: a review of current data and potential applications on risk stratification and management

S Susanibar‐Adaniya, SK Barta - American journal of …, 2021 - Wiley Online Library
Diffuse large B cell lymphoma (DLBCL), the most common type of Non‐Hodgkin lymphoma
(NHL), comprises a heterogeneous group of diseases with different biology, clinical …

Rituximab in B-cell hematologic malignancies: a review of 20 years of clinical experience

G Salles, M Barrett, R Foà, J Maurer, S O'Brien… - Advances in …, 2017 - Springer
Rituximab is a human/murine, chimeric anti-CD20 monoclonal antibody with established
efficacy, and a favorable and well-defined safety profile in patients with various CD20 …

Single-agent mosunetuzumab shows durable complete responses in patients with relapsed or refractory B-cell lymphomas: phase I dose-escalation study

LE Budde, S Assouline, LH Sehn… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Mosunetuzumab is a bispecific antibody targeting CD20 and CD3 that redirects T
cells to engage and eliminate malignant B cells and is being developed for relapsed or …

Lisocabtagene maraleucel as second-line therapy in adults with relapsed or refractory large B-cell lymphoma who were not intended for haematopoietic stem cell …

A Sehgal, D Hoda, PA Riedell, N Ghosh… - The Lancet …, 2022 - thelancet.com
Background Patients with relapsed or refractory large B-cell lymphoma after first-line
treatment who are not intended for haematopoietic stem-cell transplantation (HSCT) have …

New agents and regimens for diffuse large B cell lymphoma

L Wang, L Li, KH Young - Journal of hematology & oncology, 2020 - Springer
As a widely recognized standard regimen, R-CHOP (rituximab plus cyclophosphamide,
doxorubicin, vincristine, and prednisone) is able to cure two-thirds patients with diffuse large …

Simplified geriatric assessment in older patients with diffuse large B-cell lymphoma: the prospective elderly project of the Fondazione Italiana Linfomi

F Merli, S Luminari, A Tucci, A Arcari… - Journal of clinical …, 2021 - ascopubs.org
PURPOSE To prospectively validate the use of a simplified geriatric assessment (sGA) at
diagnosis and to integrate it into a prognostic score for older patients with diffuse large B-cell …

CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7 …

YH Huang, K Cai, PP Xu, L Wang, CX Huang… - … and Targeted Therapy, 2021 - nature.com
Epigenetic alterations play an important role in tumor progression of diffuse large B-cell
lymphoma (DLBCL). However, the biological relevance of epigenetic gene mutations on …

Diffuse large B-cell lymphoma: optimizing outcome in the context of clinical and biologic heterogeneity

LH Sehn, RD Gascoyne - Blood, The Journal of the American …, 2015 - ashpublications.org
Although the majority of patients with diffuse large B-cell lymphoma (DLBCL) can be cured
with standard rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R …

CAR T-cell therapy for B-cell lymphomas: clinical trial results of available products

JC Chavez, C Bachmeier… - Therapeutic …, 2019 - journals.sagepub.com
Adoptive cellular immunotherapy with chimeric antigen receptor (CAR) T cell has changed
the treatment landscape of B-cell non-Hodgkin's lymphoma (NHL), especially for aggressive …

Diffuse large B-cell lymphoma (DLBCL): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

H Tilly, MG Da Silva, U Vitolo, A Jack… - Annals of …, 2015 - annalsofoncology.org
Diffuse large B-cell lymphoma (DLBCL) constitutes 30%–58% of non-Hodgkin's lymphoma
series. The crude incidence in Europe is 3.8/100 000/year [1]. The incidence increases with …