Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Our ability to assess the threat posed by the genetic load to small and declining populations
has been greatly improved by advances in genome sequencing and computational …

Although detrimental genetic processes are known to adversely affect the viability of
populations, little is known about how detrimental genetic processes in a keystone species …

Deleterious genetic variation is abundant in wild populations, and understanding the
ecological and conservation implications of such variation is an area of active research …

Typically much smaller in number than their mainland counterparts, island populations are
ideal systems to investigate genetic threats to small populations. The Svalbard reindeer …

For small and isolated populations, the increased chance of mating between related
individuals can result in a substantial reduction in individual and population fitness. Despite …

Small and isolated wildlife populations face numerous threats to extinction, among which is
the deterioration of fitness due to an accumulation of deleterious genetic variation. Genomic …

Current rates of habitat degradation and climate change are causing unprecedented
declines in global biodiversity. Studies on vertebrates highlight how conservation genomics …

Genomic studies of species threatened by extinction are providing crucial information about
evolutionary mechanisms and genetic consequences of population declines and …

In efforts to prevent extinction, resource managers are often tasked with increasing genetic
diversity in a population of concern to prevent inbreeding depression or improve adaptive …