Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD)

P Upadhyay, CW Wu, A Pham, AA Zeki… - Journal of Toxicology …, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, and its global health burden is increasing. COPD is characterized by …

Household air pollution and COPD: cause and effect or confounding by other aspects of poverty?

K Mortimer, M Montes de Oca, S Salvi… - … of Tuberculosis and …, 2022 - ingentaconnect.com
SETTING: Household air pollution (HAP) and chronic obstructive pulmonary disease
(COPD) are both major public health problems, reported to cause around 4 million and 3 …

Fine particulate matter contributes to COPD-like pathophysiology: experimental evidence from rats exposed to diesel exhaust particles

Z Fang, Z Wang, Z Chen, Y Peng, Y Fu, Y Yang… - Respiratory …, 2024 - Springer
Background Ambient fine particulate matter (PM2. 5) is considered a plausible contributor to
the onset of chronic obstructive pulmonary disease (COPD). Mechanistic studies are needed …

Therapeutic properties of Punica granatum L (pomegranate) and its applications in lung‐based diseases: A detailed review

SB Shaikh, YP Bhandary - Journal of Food Biochemistry, 2021 - Wiley Online Library
Respiratory diseases are the prime cause of death and disability worldwide. The majority of
lung‐based diseases are resistant to treatment. Hence, research on unique …

Clinical application of forced oscillation technique (FOT) in early detection of airway changes in smokers

P Bhattarai, S Myers, C Chia, HC Weber… - Journal of clinical …, 2020 - mdpi.com
The forced oscillation technique (FOT) is a non-invasive method to assess airway function
by emitting oscillatory signals into the respiratory tract during tidal ventilation. This opinion …

Small airways disease in chronic obstructive pulmonary disease

N Lazarinis, E Fouka, A Linden… - Expert Review of …, 2024 - Taylor & Francis
Introduction Small airway disease (SAD) represents a common and critical feature of
Chronic Obstructive Pulmonary Disease (COPD). Introduced in the'60s, SAD has gradually …

The relevance of targeting treatment to small airways in asthma and COPD

P Santus, D Radovanovic, M Pecchiari… - Respiratory …, 2020 - rc.rcjournal.com
COPD and asthma have different risk factors and pathogenesis, but they share a
pathophysiologic hallmark characterized by small airways disease. Although difficult to …

Inflammatory biomarkers interleukin 1 beta (IL-1β) and tumour necrosis factor alpha (TNF-α) are differentially elevated in tobacco smoke associated COPD and …

B Shyam Prasad Shetty, SK Chaya, S Kumar V… - Toxics, 2021 - mdpi.com
Chronic obstructive pulmonary disease (COPD), the leading cause of mortality and morbidity
worldwide, is characterized by abnormal activation of inflammatory cells. The increased pro …

Smoke exposure from chronic biomass burning induces distinct accumulative systemic inflammatory cytokine alterations compared to tobacco smoking in healthy …

R Falfán-Valencia, A Ramírez-Venegas… - Cytokine, 2020 - Elsevier
Long-term exposure to biomass-burning smoke (BS) is associated with chronic obstructive
pulmonary disease (COPD), asthma, and other chronic inflammatory lung diseases. BS …

The “slow horse racing effect” on lung function in adult life in chronic obstructive pulmonary disease associated to biomass exposure

A Ramírez-Venegas, F Montiel-Lopez… - Frontiers in …, 2021 - frontiersin.org
Although different trajectories in lung function decline have been identified in patients with
COPD associated to tobacco exposure (TE-COPD), genetic, environmental, and infectious …