Multifunctional gold nanoparticles for improved diagnostic and therapeutic applications: a review

NRS Sibuyi, KL Moabelo, AO Fadaka, S Meyer… - Nanoscale Research …, 2021 - Springer
The medical properties of metals have been explored for centuries in traditional medicine for
the treatment of infections and diseases and still practiced to date. Platinum-based drugs are …

Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy

AM Angelidi, MJ Belanger, A Kokkinos… - Endocrine …, 2022 - academic.oup.com
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

[HTML][HTML] SCD1 is the critical signaling hub to mediate metabolic diseases: Mechanism and the development of its inhibitors

Q Sun, X Xing, H Wang, K Wan, R Fan, C Liu… - Biomedicine & …, 2024 - Elsevier
Metabolic diseases, featured with dysregulated energy homeostasis, have become major
global health challenges. Patients with metabolic diseases have high probability to manifest …

[HTML][HTML] The obesity-autophagy-cancer axis: Mechanistic insights and therapeutic perspectives

AB Behrooz, M Cordani, A Fiore, M Donadelli… - Seminars in Cancer …, 2024 - Elsevier
Autophagy, a self-degradative process vital for cellular homeostasis, plays a significant role
in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex …

Tumor microenvironment and nanotherapeutics: intruding the tumor fort

AVVVR Kiran, GK Kumari, PT Krishnamurthy… - Biomaterials …, 2021 - pubs.rsc.org
Over recent years, advancements in nanomedicine have allowed new approaches to
diagnose and treat tumors. Nano drug delivery systems exploit the enhanced permeability …

Targeted delivery of nutraceuticals derived from food for the treatment of obesity and its related complications

Z Dai, Y Zhang, Y Meng, S Li, Z Suonan, Y Sun, J Ji… - Food Chemistry, 2023 - Elsevier
Nutraceuticals which are abundant in foods have attracted much attention due to their
bioactive activities of anti-obesity, anti-hyperlipidemia and anti-atherosclerosis …

Hyaluronic acid-graphene oxide quantum dots nanoconjugate as dual purpose drug delivery and therapeutic agent in meta-inflammation

K Sarkar, S Bank, A Chatterjee, K Dutta, A Das… - Journal of …, 2023 - Springer
Type 2 diabetes mellitus (T2DM) predominantly considered a metabolic disease is now
being considered an inflammatory disease as well due to the involvement of meta …

[HTML][HTML] Potentialities of nanomaterials for the management and treatment of metabolic syndrome: A new insight

CO Adetunji, OS Michael, S Rathee, KRB Singh… - Materials today …, 2022 - Elsevier
Metabolic syndrome is a collection of abnormalities including insulin resistance,
hypertension, dyslipidemia, type 2 diabetes, obesity, inflammation, non-alcoholic fatty liver …

Functional nanomedicines for targeted therapy of bladder cancer

C Tang, H Liu, Y Fan, J He, F Li, J Wang… - Frontiers in …, 2021 - frontiersin.org
Bladder cancer is one of most common malignant urinary tract tumor types with high
incidence worldwide. In general, transurethral resection of non-muscle-invasive bladder …

Tackling dyslipidemia in obesity from a nanotechnology perspective

LM Trandafir, G Dodi, O Frasinariu, AC Luca… - Nutrients, 2022 - mdpi.com
Obesity and dyslipidemia are the main features of metabolic syndrome, expressed mainly by
adipose tissue dysfunction and connected by similar pathways and pharmacotherapy …