Dental follicle cells (DFCs) are a group of mesenchymal progenitor cells surrounding the
tooth germ, responsible for cementum, periodontal ligament, and alveolar bone formation in …

Abstract TRPM4 is a Ca 2+-activated nonselective cation channel. The channel is activated
by an increase of intracellular Ca 2+ and is regulated by several factors including …

Background Obesity is characterized by increased adipose tissue mass that results from
increased fat cell size (hypertrophy) and number (hyperplasia). The molecular mechanisms …

Transient receptor potential melastatin 4 (TRPM4) is a unique member of the TRPM protein
family and, similarly to TRPM5, is Ca2+ sensitive and permeable for monovalent but not …

Cardiac fibroblasts play an important role in cardiac matrix turnover and are involved in
cardiac fibrosis development. Ca 2+ is a driving belt in this phenomenon. This study …

Tooth root development involves intricate spatiotemporal cellular dynamics and molecular
regulation. The initiation of Hertwig's epithelial root sheath (HERS) induces odontoblast …

Transient receptor potential (TRP) ion channels are cationic permeable proteins located on
the plasma membrane. TRPs are cellular sensors for perceiving diverse physical and/or …

Intracellular Ca2+ signals are essential for stem cell function and play a significant role in
the differentiation process. Dental pulp stem cells (DPSCs) are a potential source of stem …

Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cells derived from dental
pulp that serves as an important model for investigating biological regeneration. DPSCs …

Biomaterials and stem cells are essential components in the field of regenerative medicine.
Various biomaterials have been designed that have appropriate biochemical and …