Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission
S Karthikeyan, JI Levy, P De Hoff, G Humphrey… - Nature, 2022 - nature.com
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical
for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at …
for public health interventions. Inferring lineage prevalence by clinical testing is infeasible at …
Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale
SARS-CoV-2 surveillance by wastewater-based epidemiology is poised to provide a
complementary approach to sequencing individual cases. However, robust quantification of …
complementary approach to sequencing individual cases. However, robust quantification of …
Unlocking capacities of genomics for the COVID-19 response and future pandemics
During the COVID-19 pandemic, genomics and bioinformatics have emerged as essential
public health tools. The genomic data acquired using these methods have supported the …
public health tools. The genomic data acquired using these methods have supported the …
Genetic diversity and evolutionary convergence of cryptic SARS-CoV-2 lineages detected via wastewater sequencing
DA Gregory, M Trujillo, C Rushford, A Flury… - PLoS …, 2022 - journals.plos.org
Wastewater-based epidemiology (WBE) is an effective way of tracking the appearance and
spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we …
spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we …
Nationwide trends in COVID-19 cases and SARS-CoV-2 RNA wastewater concentrations in the United States
Wastewater-based epidemiology has emerged as a promising technology for population-
level surveillance of COVID-19. In this study, we present results of a large nationwide SARS …
level surveillance of COVID-19. In this study, we present results of a large nationwide SARS …
Early detection and surveillance of SARS-CoV-2 genomic variants in wastewater using COJAC
K Jahn, D Dreifuss, I Topolsky, A Kull… - Nature …, 2022 - nature.com
The continuing emergence of SARS-CoV-2 variants of concern and variants of interest
emphasizes the need for early detection and epidemiological surveillance of novel variants …
emphasizes the need for early detection and epidemiological surveillance of novel variants …
Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater
Over the course of the COVID-19 pandemic, variants of SARS-CoV-2 have emerged that are
more contagious and more likely to cause breakthrough infections. Targeted amplicon …
more contagious and more likely to cause breakthrough infections. Targeted amplicon …
New prospects of environmental RNA metabarcoding research in biological diversity, ecotoxicological monitoring, and detection of COVID-19: a critical review
Ecosystems are multifaceted and complex systems and understanding their composition is
crucial for the implementation of efficient conservation and management. Conventional …
crucial for the implementation of efficient conservation and management. Conventional …
SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programs
AX Han, A Toporowski, JA Sacks, MD Perkins… - Nature Genetics, 2023 - nature.com
The first step in SARS-CoV-2 genomic surveillance is testing to identify people who are
infected. However, global testing rates are falling as we emerge from the acute health …
infected. However, global testing rates are falling as we emerge from the acute health …
Monkeypox viral nucleic acids detected using both DNA and RNA extraction workflows
ME Sharkey, KM Babler, BS Shukla, SM Abelson… - Science of The Total …, 2023 - Elsevier
Molecular methods have been used to detect human pathogens in wastewater with
sampling typically performed at wastewater treatment plants (WWTP) and upstream …
sampling typically performed at wastewater treatment plants (WWTP) and upstream …