[HTML][HTML] Pathomechanisms and therapeutic opportunities in radiation-induced heart disease: from bench to bedside

M Sárközy, Z Varga, R Gáspár, G Szűcs… - Clinical Research in …, 2021 - Springer
Cancer management has undergone significant improvements, which led to increased long-
term survival rates among cancer patients. Radiotherapy (RT) has an important role in the …

Actions and potential therapeutic applications of growth hormone–releasing hormone agonists

AV Schally, X Zhang, R Cai, JM Hare, R Granata… - …, 2019 - academic.oup.com
In this article, we briefly review the identification of GHRH, provide an abridged overview of
GHRH antagonists, and focus on studies with GHRH agonists. Potent GHRH agonists of JI …

The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors

SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Agonistic analog of growth hormone–releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke

Y Liu, J Yang, X Che, J Huang… - Proceedings of the …, 2021 - National Acad Sciences
Ischemic stroke can induce neurogenesis. However, most stroke-generated newborn
neurons cannot survive. It has been shown that MR-409, a potent synthetic agonistic analog …

Scavenging of reactive oxygen species can adjust the differentiation of tendon stem cells and progenitor cells and prevent ectopic calcification in tendinopathy

H Shen, L Cheng, Q Zheng, W Liu, Y Wang - Acta Biomaterialia, 2022 - Elsevier
Tendinopathy is a common disorder that leads to pain and impaired quality of life. Recent
studies revealed that osteogenic differentiation of tendon stem/progenitor cells (TSPCs) …

[HTML][HTML] Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2

EN Gurzov, M Tran, MA Fernandez-Rojo, TL Merry… - Cell metabolism, 2014 - cell.com
Hepatic insulin resistance is a key contributor to the pathogenesis of obesity and type 2
diabetes (T2D). Paradoxically, the development of insulin resistance in the liver is not …

[HTML][HTML] Intramyocardial delivery of mesenchymal stem cell-seeded hydrogel preserves cardiac function and attenuates ventricular remodeling after myocardial …

E Mathieu, G Lamirault, C Toquet, P Lhommet… - PloS one, 2012 - journals.plos.org
Background To improve the efficacy of bone marrow-derived mesenchymal stem cell (MSC)
therapy targeted to infarcted myocardium, we investigated whether a self-setting silanized …

Micro-ultrasound for preclinical imaging

FS Foster, J Hossack, SL Adamson - Interface focus, 2011 - royalsocietypublishing.org
Over the past decade, non-invasive preclinical imaging has emerged as an important tool to
facilitate biomedical discovery. Not only have the markets for these tools accelerated, but the …

S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells

SA Gomes, EB Rangel, C Premer… - Proceedings of the …, 2013 - National Acad Sciences
Although nitric oxide (NO) signaling promotes differentiation and maturation of endothelial
progenitor cells, its role in the differentiation of mesenchymal stem cells (MSCs) into …

Acromegaly induced by ectopic secretion of GHRH: a review 30 years after GHRH discovery

F Borson-Chazot, L Garby, G Raverot, F Claustrat… - Annales d' …, 2012 - Elsevier
Ectopic acromegaly is very rare and since the discovery of growth hormone-releasing
hormone (GHRH), 30 years ago, only 74 cases have been reported in the literature. Except …