[HTML][HTML] Pathomechanisms and therapeutic opportunities in radiation-induced heart disease: from bench to bedside
Cancer management has undergone significant improvements, which led to increased long-
term survival rates among cancer patients. Radiotherapy (RT) has an important role in the …
term survival rates among cancer patients. Radiotherapy (RT) has an important role in the …
Actions and potential therapeutic applications of growth hormone–releasing hormone agonists
In this article, we briefly review the identification of GHRH, provide an abridged overview of
GHRH antagonists, and focus on studies with GHRH agonists. Potent GHRH agonists of JI …
GHRH antagonists, and focus on studies with GHRH agonists. Potent GHRH agonists of JI …
The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors
SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
Agonistic analog of growth hormone–releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke
Y Liu, J Yang, X Che, J Huang… - Proceedings of the …, 2021 - National Acad Sciences
Ischemic stroke can induce neurogenesis. However, most stroke-generated newborn
neurons cannot survive. It has been shown that MR-409, a potent synthetic agonistic analog …
neurons cannot survive. It has been shown that MR-409, a potent synthetic agonistic analog …
Scavenging of reactive oxygen species can adjust the differentiation of tendon stem cells and progenitor cells and prevent ectopic calcification in tendinopathy
H Shen, L Cheng, Q Zheng, W Liu, Y Wang - Acta Biomaterialia, 2022 - Elsevier
Tendinopathy is a common disorder that leads to pain and impaired quality of life. Recent
studies revealed that osteogenic differentiation of tendon stem/progenitor cells (TSPCs) …
studies revealed that osteogenic differentiation of tendon stem/progenitor cells (TSPCs) …
[HTML][HTML] Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2
EN Gurzov, M Tran, MA Fernandez-Rojo, TL Merry… - Cell metabolism, 2014 - cell.com
Hepatic insulin resistance is a key contributor to the pathogenesis of obesity and type 2
diabetes (T2D). Paradoxically, the development of insulin resistance in the liver is not …
diabetes (T2D). Paradoxically, the development of insulin resistance in the liver is not …
[HTML][HTML] Intramyocardial delivery of mesenchymal stem cell-seeded hydrogel preserves cardiac function and attenuates ventricular remodeling after myocardial …
E Mathieu, G Lamirault, C Toquet, P Lhommet… - PloS one, 2012 - journals.plos.org
Background To improve the efficacy of bone marrow-derived mesenchymal stem cell (MSC)
therapy targeted to infarcted myocardium, we investigated whether a self-setting silanized …
therapy targeted to infarcted myocardium, we investigated whether a self-setting silanized …
Micro-ultrasound for preclinical imaging
Over the past decade, non-invasive preclinical imaging has emerged as an important tool to
facilitate biomedical discovery. Not only have the markets for these tools accelerated, but the …
facilitate biomedical discovery. Not only have the markets for these tools accelerated, but the …
S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells
Although nitric oxide (NO) signaling promotes differentiation and maturation of endothelial
progenitor cells, its role in the differentiation of mesenchymal stem cells (MSCs) into …
progenitor cells, its role in the differentiation of mesenchymal stem cells (MSCs) into …
Acromegaly induced by ectopic secretion of GHRH: a review 30 years after GHRH discovery
F Borson-Chazot, L Garby, G Raverot, F Claustrat… - Annales d' …, 2012 - Elsevier
Ectopic acromegaly is very rare and since the discovery of growth hormone-releasing
hormone (GHRH), 30 years ago, only 74 cases have been reported in the literature. Except …
hormone (GHRH), 30 years ago, only 74 cases have been reported in the literature. Except …