Nanoparticles as drug delivery systems: a review of the implication of nanoparticles' physicochemical properties on responses in biological systems

A Yusuf, ARZ Almotairy, H Henidi, OY Alshehri… - Polymers, 2023 - mdpi.com
In the last four decades, nanotechnology has gained momentum with no sign of slowing
down. The application of inventions or products from nanotechnology has revolutionised all …

The pharmacokinetics of vitamin C

J Lykkesfeldt, P Tveden-Nyborg - Nutrients, 2019 - mdpi.com
The pharmacokinetics of vitamin C (vitC) is indeed complex. Regulated primarily by a family
of saturable sodium dependent vitC transporters (SVCTs), the absorption and elimination …

Nanoparticle-mediated combination therapy: two-in-one approach for cancer

S Gurunathan, MH Kang, M Qasim, JH Kim - International journal of …, 2018 - mdpi.com
Cancer represents a group of heterogeneous diseases characterized by uncontrolled
growth and spread of abnormal cells, ultimately leading to death. Nanomedicine plays a …

Targeting ferroptosis against ischemia/reperfusion cardiac injury

J Lillo-Moya, C Rojas-Solé, D Muñoz-Salamanca… - Antioxidants, 2021 - mdpi.com
Ischemic heart disease is a leading cause of death worldwide. Primarily, ischemia causes
decreased oxygen supply, resulting in damage of the cardiac tissue. Naturally …

Vitamin C and cardiovascular disease: an update

MB Morelli, J Gambardella, V Castellanos, V Trimarco… - Antioxidants, 2020 - mdpi.com
The potential beneficial effects of the antioxidant properties of vitamin C have been
investigated in a number of pathological conditions. In this review, we assess both clinical …

Effectiveness of some vitamins in the prevention of cardiovascular disease: a narrative review

AK Shah, NS Dhalla - Frontiers in Physiology, 2021 - frontiersin.org
By virtue of their regulatory role in various metabolic and biosynthetic pathways for energy
status and cellular integrity, both hydro-soluble and lipo-soluble vitamins are considered to …

Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability

S Gopi, P Balakrishnan - Journal of liposome research, 2021 - Taylor & Francis
The aim of this study was to evaluate the oral bioavailability of liposomal vitamin C and non-
liposomal vitamin C in healthy, adult, human subjects under fasting conditions through an …

New oral liposomal vitamin C formulation: Properties and bioavailability

M Łukawski, P Dałek, T Borowik, A Foryś… - Journal of liposome …, 2020 - Taylor & Francis
Vitamin C is the exogenous compound necessary for a variety of metabolic processes;
therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C …

[HTML][HTML] Nano-vitamin C: A promising candidate for therapeutic applications

T Bedhiafi, S Idoudi, Q Fernandes, L Al-Zaidan… - Biomedicine & …, 2023 - Elsevier
Vitamin C is an important nutrient implicated in different physiological functions in humans.
Despite its important biological functions, therapeutic applications of vitamin C are rare and …

[HTML][HTML] Molecular Pharmacology of Vitamin C and Relevance to Health and Obesity—A Narrative Review

RB Wilson, Y Liang, D Kaushal, A Carr - International journal of molecular …, 2024 - mdpi.com
The role of food constituents as pharmacological agents is an important consideration in
health and obesity. Vitamin C acts as a small molecule antioxidant but is also a co-factor for …