Active surveillance of metastatic renal cell carcinoma: Results from a prospective observational study (MaRCC)

MR Harrison, BA Costello, NA Bhavsar… - Cancer, 2021 - Wiley Online Library
Background Systemic therapy (ST) can be deferred in patients who have metastatic renal
cell carcinoma (mRCC) and slow‐growing metastases. Currently, this subset of patients …

Overall survival improvement in patients with metastatic clear-cell renal cell carcinoma between 2000 and 2020: a retrospective cohort study

S Demasure, I Spriet, PR Debruyne, A Laenen… - Acta …, 2022 - Taylor & Francis
Background Only a few recent phase III trials with targeted therapies or immune checkpoint
inhibitors (ICIs) in metastatic clear-cell renal cell carcinoma (m-ccRCC) demonstrated an …

[HTML][HTML] Treatment of advanced renal cell carcinoma: immunotherapies have demonstrated overall survival benefits while targeted therapies have not

O Hemminki, N Perlis, J Bjorklund, A Finelli… - European urology open …, 2020 - Elsevier
Context Current guidelines suggest several targeted therapies (TTs) and immunotherapies
(ITs) in the treatment of advanced or metastatic renal cell carcinoma (mRCC). Ideal …

Progress in survival in renal cell carcinoma through 50 years evaluated in Finland and Sweden

K Hemminki, A Försti, A Hemminki, B Ljungberg… - PLoS …, 2021 - journals.plos.org
Global survival studies have shown favorable development in renal cell carcinoma (RCC)
treatment but few studies have considered extended periods or covered populations for …

[HTML][HTML] Clinical T1a Renal Cell Carcinoma, Not Always a Harmless Disease—A National Register Study

T Almdalal, P Sundqvist, U Harmenberg… - European Urology Open …, 2022 - Elsevier
Background T1a renal cell carcinoma (RCC) is typically considered a curable disease,
irrespective of the choice of local treatment modality. Objective To identify factors associated …

Insulin receptor expression to predict resistance to axitinib and elucidation of the underlying molecular mechanism in metastatic renal cell carcinoma

M Takahashi, K Daizumoto, T Fukawa… - British Journal of …, 2023 - nature.com
Background The study aimed to examine the significance of insulin receptor (INSR)
expression in predicting resistance to axitinib in clear cell renal cell carcinoma (ccRCC) …

[HTML][HTML] Changes in treatment reality and survival of patients with advanced clear cell renal cell carcinoma–analyses from the german clinical RCC-registry

PJ Goebell, M Staehler, L Müller, A Nusch… - Clinical Genitourinary …, 2018 - Elsevier
Introduction Because the treatment landscape for metastatic renal cell carcinoma (mRCC)
has evolved dramatically over the past decade, data on patients' treatment and outcomes in …

Comparative survival associated with use of targeted vs nontargeted therapy in medicare patients with metastatic renal cell carcinoma

P Li, J Jahnke, AR Pettit, YN Wong… - JAMA Network …, 2019 - jamanetwork.com
Importance Targeted therapies for advanced renal cell carcinoma (RCC) have shown
increased tolerability and survival advantages over older treatments in clinical trials, but …

[HTML][HTML] The difference in the survival rate of patients with metastatic renal cell carcinoma in the intermediate-risk group of the Memorial Sloan Kettering Cancer Center …

S Tamada, T Iguchi, S Yasuda, M Kato, T Yamasaki… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The difference in the survival rate of patients with metastatic renal cell carcinoma in the
intermediate-risk group of the Memorial Sloan Kettering Cancer Center criteria - PMC Back to …

Perivascular neuropilin‐1 expression is an independent marker of improved survival in renal cell carcinoma

E Morin, C Lindskog, M Johansson… - The Journal of …, 2020 - Wiley Online Library
Renal cell carcinoma (RCC) treatment has improved in the last decade with the introduction
of drugs targeting tumor angiogenesis. However, the 5‐year survival of metastatic disease is …