Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …

Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …

Abstract Background Three-dimensional (3D) imaging mass spectrometry (MS) is an
analytical chemistry technique for the 3D molecular analysis of a tissue specimen, entire …

We propose a methodology to select essential spectral pixels (ESPs) of chemical images.
These pixels are on the outer envelope of the principal component scores of the data and …

An approach is proposed and illustrated for the joint selection of essential samples and
essential variables of a data matrix in the frame of spectral unmixing. These essential …

Since biology is by and large a 3-dimensional phenomenon, it is hardly surprising that 3D
imaging has had a significant impact on many challenges in the life sciences. Imaging mass …

Principal component analysis (PCA) and other multivariate analysis methods have been
used increasingly to analyse and understand depth profiles in X‐ray photoelectron …

The 'curse of dimensionality'imposes fundamental limits on the analysis of the large,
information rich datasets that are produced by mass spectrometry imaging. Additionally …

We present a subspace method that accelerates data acquisition using Fourier transform-ion
cyclotron resonance (FT-ICR) mass spectrometry imaging (MSI). For MSI of biological tissue …