Given the expanding elderly population in the United States and the world, it is important to
understand the processes underlying both natural and pathological age-related changes in …

Topical treatment of vitreoretinal diseases remains a challenge due to slow corneal uptake
and systemic clearance. Exosomes are emerging nanocarriers for drug delivery due to …

Quantifying the full 3-D shape of the human crystalline lens is important for improving
intraocular lens power or sizing calculations in treatments of cataract and presbyopia. In a …

Purpose To study the growth model, shape, and developmental relationship of lens and
eyeball, we used two-dimensional Magnetic Resonance (MR) imaging to investigate …

Background The shape and microstructure of the human crystalline lens alter with ageing,
and this has an effect on the optical properties of the eye. The aim of this study was to …

The purpose of this study was to investigate how the mechanical properties and geometry of
the lens influence the changes in lens shape during accommodation. To do so, ex vivo …

METHODS A Chinese population-based retrospective study was performed. A total of 497
individuals (490 right eyes and 495 left eyes), ranging from 3 to 69 years old were included …

The crystalline lens is an important optical element in the eye, responsible for focusing, and
which experiences significant changes throughout life. The shape of the lens is usually …

Quantifying human crystalline lens geometry as a function of age and accommodation is
important for improved cataract and presbyopia treatments. In previous works we presented …

It is well known that human crystalline lens shape, dimensions and optical properties
change throughout life and influence whole eye refraction. However, it is not clear if lens …