The role of AGE/RAGE signaling in diabetes‐mediated vascular calcification
AM Kay, CLS Simpson… - Journal of diabetes …, 2016 - Wiley Online Library
AGE/RAGE signaling has been a well‐studied cascade in many different disease states,
particularly diabetes. Due to the complex nature of the receptor and multiple intersecting …
particularly diabetes. Due to the complex nature of the receptor and multiple intersecting …
A review of protein adsorption on bioceramics
K Wang, C Zhou, Y Hong, X Zhang - Interface focus, 2012 - royalsocietypublishing.org
Bioceramics, because of its excellent biocompatible and mechanical properties, has always
been considered as the most promising materials for hard tissue repair. It is well know that …
been considered as the most promising materials for hard tissue repair. It is well know that …
Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass
The strength of bone depends on bone quantity and quality. Osteocalcin (Ocn) is the most
abundant noncollagenous protein in bone and is produced by osteoblasts. It has been …
abundant noncollagenous protein in bone and is produced by osteoblasts. It has been …
Accurate force field parameters and pH resolved surface models for hydroxyapatite to understand structure, mechanics, hydration, and biological interfaces
Mineralization of bone and teeth involves interactions between biomolecules and
hydroxyapatite. Associated complex interfaces and processes remain difficult to analyze at …
hydroxyapatite. Associated complex interfaces and processes remain difficult to analyze at …
Simulations of inorganic–bioorganic interfaces to discover new materials: insights, comparisons to experiment, challenges, and opportunities
H Heinz, H Ramezani-Dakhel - Chemical Society Reviews, 2016 - pubs.rsc.org
Natural and man-made materials often rely on functional interfaces between inorganic and
organic compounds. Examples include skeletal tissues and biominerals, drug delivery …
organic compounds. Examples include skeletal tissues and biominerals, drug delivery …
Polypeptide self-assemblies: nanostructures and bioapplications
Polypeptide copolymers can self-assemble into diverse aggregates. The morphology and
structure of aggregates can be varied by changing molecular architectures, self-assembling …
structure of aggregates can be varied by changing molecular architectures, self-assembling …
Intrinsically disordered proteins and biomineralization
AL Boskey, E Villarreal-Ramirez - Matrix Biology, 2016 - Elsevier
In vertebrates and invertebrates, biomineralization is controlled by the cell and the proteins
they produce. A large number of these proteins are intrinsically disordered, gaining some …
they produce. A large number of these proteins are intrinsically disordered, gaining some …
Molecular mechanisms for intrafibrillar collagen mineralization in skeletal tissues
The critical role of the self-assembled structure of collagen in skeletal mineralization is long
recognized, yet the angstrom to tens of nanometers length-scale nucleation mechanism of …
recognized, yet the angstrom to tens of nanometers length-scale nucleation mechanism of …
Biopolymer/calcium phosphate scaffolds for bone tissue engineering
With nearly 30 years of progress, tissue engineering has shown promise in developing
solutions for tissue repair and regeneration. Scaffolds, together with cells and growth factors …
solutions for tissue repair and regeneration. Scaffolds, together with cells and growth factors …
Natural protein bioinspired materials for regeneration of hard tissues
X Xu, X Chen, J Li - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The regenerative materials for hard tissues, ie tooth (enamel, dentin, and cementum) and
bone, require extremely high standards in terms of their mechanical properties …
bone, require extremely high standards in terms of their mechanical properties …