Tranexamic acid for the prevention of postpartum hemorrhage in women undergoing cesarean delivery: an updated meta-analysis

I Bellos, V Pergialiotis - American Journal of Obstetrics and Gynecology, 2022 - Elsevier
Objective This study aimed to assess the efficacy and safety of prophylactic tranexamic acid
administration vs standard uterotonic agents alone among women undergoing cesarean …

Epidemiology and definition of PPH worldwide

J Bláha, T Bartošová - Best Practice & Research Clinical Anaesthesiology, 2022 - Elsevier
Highlights•Poor PPH outcomes are considered preventable in many cases, and are often
attributed to delayed recognition or inappropriate treatment.•Currently used definitions of …

Machine learning approach for the prediction of postpartum hemorrhage in vaginal birth

M Akazawa, K Hashimoto, N Katsuhiko, Y Kaname - Scientific reports, 2021 - nature.com
Postpartum hemorrhage is the leading cause of maternal morbidity. Clinical prediction of
postpartum hemorrhage remains challenging, particularly in the case of a vaginal birth. We …

Shock index as a predictor of postpartum haemorrhage after vaginal delivery: Secondary analysis of a multicentre randomised controlled trial

H Madar, C Deneux‐Tharaux… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Objective To describe the shock index (SI) distribution during the first 2 hours after delivery
and to evaluate its performance when measured 15 and 30 minutes after delivery for …

Postpartum hemorrhage—Epidemiology, risk factors, and causes

K Patek, P Friedman - Clinical obstetrics and gynecology, 2023 - journals.lww.com
The incidence of postpartum hemorrhage (PPH) is increasing worldwide and in the United
States. Coinciding, is the increased rate of severe maternal morbidity with blood transfusion …

Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage

D Westergaard, V Steinthorsdottir, L Stefansdottir… - Nature Genetics, 2024 - nature.com
Bleeding in early pregnancy and postpartum hemorrhage (PPH) bear substantial risks, with
the former closely associated with pregnancy loss and the latter being the foremost cause of …

Current state and future direction of postpartum hemorrhage risk assessment

HB Ende, AJ Butwick - Obstetrics & Gynecology, 2021 - journals.lww.com
In the United States, postpartum hemorrhage is a leading preventable cause of maternal
mortality and morbidity. To reduce morbidity from postpartum hemorrhage, risk assessment …

Hemostatic biomarkers associated with postpartum hemorrhage: a systematic review and meta-analysis

C de Moreuil, D Mehic, S Nopp, D Kraemmer… - Blood …, 2023 - ashpublications.org
Postpartum hemorrhage (PPH) is a leading cause of maternal morbi-mortality. Although
obstetric risk factors are well described, the impact of predelivery hematologic and …

Women with severe postpartum hemorrhage have a decreased endogenous thrombin potential before delivery

C de Moreuil, Y Dargaud, C Nougier, PF Dupré… - Journal of Thrombosis …, 2023 - Elsevier
Background Severe postpartum hemorrhage (PPH), defined as a blood loss≥ 1000 mL, is
associated with maternal morbidity and mortality. Objectives We aimed at characterizing …

Improving postpartum hemorrhage risk prediction using longitudinal electronic medical records

AB Zheutlin, L Vieira, RA Shewcraft, S Li… - Journal of the …, 2022 - academic.oup.com
Objective Postpartum hemorrhage (PPH) remains a leading cause of preventable maternal
mortality in the United States. We sought to develop a novel risk assessment tool and …