Dendritic cells (DCs) are crucial in the defence against pathogens. Invading pathogens are
recognized by Toll-like receptors (TLRs) and receptors such as C-type lectins expressed on …

The dendritic cell (DC)-specific HIV-1 receptor DC-SIGN plays a key-role in the
dissemination of HIV-1 by DCs. DC-SIGN captures HIV-1 at sites of entry, enabling its …

Ebola virus is a highly lethal pathogen responsible for several outbreaks of hemorrhagic
fever. Here we show that the primate lentiviral binding C-type lectins DC-SIGN and L-SIGN …

The lectins DC-SIGN and DC-SIGNR can augment viral infection; however, the range of
pathogens interacting with these attachment factors is incompletely defined. Here we show …

The C-type lectins DC-SIGN and DC-SIGNR bind mannose-rich glycans with high affinity. In
vitro, cells expressing these attachment factors efficiently capture, and are infected by, a …

Platelets can engulf human immunodeficiency virus type 1 (HIV-1), and a significant amount
of HIV-1 in the blood of infected individuals is associated with these cells. However, it is …

The C-type lectins DC-SIGN and DC-SIGNR [collectively referred to as DC-SIGN (R)] bind
and transmit human immunodeficiency virus (HIV) and simian immunodeficiency virus to T …

To better understand the role of dendritic cells (DCs) in human immunodeficiency virus (HIV)
transmission at mucosal surfaces, we examined the expressions of the HIV adhesion …

In recent years there has been increasing interest in the diversity and function of
carbohydrates present on a range of endogenous mammalian glycoproteins and pathogen …

Antigen-presenting cells are localized in essentially every tissue, where they operate at the
interface of innate and acquired immunity by capturing pathogens and presenting pathogen …