[HTML][HTML] Role of structural and non-structural proteins and therapeutic targets of SARS-CoV-2 for COVID-19
Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …
[HTML][HTML] The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …
W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …
health, healthcare systems, and economies around the globe. Scientists are expending …
A review on drug repurposing applicable to COVID-19
S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …
cost and in a shorter time. There are different computational drug-repurposing strategies and …
[HTML][HTML] The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis
NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
[HTML][HTML] Different mutations in SARS-CoV-2 associate with severe and mild outcome
Introduction Genomic alterations in a viral genome can lead to either better or worse
outcome and identifying these mutations is of utmost importance. Here, we correlated …
outcome and identifying these mutations is of utmost importance. Here, we correlated …
A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico …
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a global …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a global …
In silico screening of hundred phytocompounds of ten medicinal plants as potential inhibitors of nucleocapsid phosphoprotein of COVID-19: an approach to prevent …
R Rolta, R Yadav, D Salaria, S Trivedi… - Journal of …, 2021 - Taylor & Francis
Currently, there is no specific treatment to cure COVID-19. Many medicinal plants have
antiviral, antioxidant, antibacterial, antifungal, anticancer, wound healing etc. Therefore, the …
antiviral, antioxidant, antibacterial, antifungal, anticancer, wound healing etc. Therefore, the …
Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …
Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
Introduction Despite all the efforts to treat COVID-19, no particular cure has been found for
this virus. Since developing antiviral drugs is a time-consuming process, the most effective …
this virus. Since developing antiviral drugs is a time-consuming process, the most effective …
3D‐QSAR, molecular docking, molecular dynamics, and ADME/T analysis of marketed and newly designed flavonoids as inhibitors of Bcl‐2 family proteins for …
A Poustforoosh, S Faramarz… - Journal of Cellular …, 2022 - Wiley Online Library
Glioblastoma is the most common and destructive brain tumor with increasing complexity.
Flavonoids are versatile natural compounds with the approved anticancer activity, which …
Flavonoids are versatile natural compounds with the approved anticancer activity, which …