Under physiological conditions, cells are in a stable state known as redox homeostasis,
which is maintained by the balance between continuous ROS/RNS generation and several …

Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative
neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and …

Patients with Sézary syndrome (SS), a leukemic variant of cutaneous T-cell lymphoma
(CTCL), are prone to Staphylococcus aureus infections and have a poor prognosis due to …

Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal
Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of …

Zinc is required for the regulation of proliferation, metabolism, and cell signaling. It is an
intracellular second messenger, and the cellular level of ionic, mobile zinc is strictly …

The advanced stages of cutaneous T cell lymphoma (CTCL) are characterized not only by
decreased levels of pro-inflammatory cytokines, resulting in high susceptibility to infections …

In the present study we analyzed the anti-proliferative effect of tocilizumab, a humanized
recombinant monoclonal interleukin 6 receptor (IL-6R) antibody, against non-small cell lung …

Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma, undergo
large-cell transformation (LCT) in the late stage, manifesting aggressive behavior, resistance …

The epithelial− mesenchymal transition (EMT) of podocytes had been reported to be
involved in the glomerular fibrosis in diabetic kidney diseases, which was regulated by TGFβ …

First-line therapy for pancreatic cancer is gemcitabine. Although tumors may initially respond
to the gemcitabine treatment, soon tumor resistance develops leading to treatment failure …