Transgenic mouse models have been used extensively to model the cognitive impairments
arising from Alzheimer's disease (AD)-related pathology. However, less is known about the …

Neurodegenerative diseases (NDs) are characterized by uncontrolled loss of neuronal cells
leading to a progressive deterioration of brain functions. The transition rate of numerous …

Oxidative damage including lipid peroxidation is widely reported in Alzheimer's disease
(AD) with the peroxidation of phospholipids in membranes being the driver of ferroptosis, an …

Alzheimer's disease (AD) is a multifaceted neurodegenerative disorder characterized by
substantial neuronal damage which manifests in the form of deficits in memory and …

Objective Alzheimer's disease (AD) is often associated with neuropsychiatric symptoms,
including agitation and aggressive behavior. These symptoms increase with disease …

Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy and aggression
affect up to 90% of Alzheimer's disease (AD) patients. These symptoms significantly …

Aims GABAergic modulation involved in cognitive processing appears to be substantially
changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to …

Background: Neuroimaging studies investigating the behavioral and psychological
symptoms of dementia (BPSD)—such as apathy, anxiety, and depression—have linked …

Alzheimer's disease is the most widespread neurodegenerative disease in the world and
produces significant adverse social-economic consequences. Despite numerous studies of …

Ciljevi: Postoje dokazi da je GABAergička modulacija uključena u kognitivne procese
značajno promenjena kod Alchajmerove bolesti (AD). U široko korišćenom 5xFAD modelu …