Cingulin–nonmuscle myosin interaction plays a role in epithelial morphogenesis and cingulin nanoscale organization

F Rouaud, M Maupérin… - Journal of Cell …, 2024 - journals.biologists.com
Cingulin (CGN) tethers nonmuscle myosin 2B (NM2B; heavy chain encoded by MYH10) to
tight junctions (TJs) to modulate junctional and apical cortex mechanics. Here, we studied …

Talin-1 variants associated with spontaneous coronary artery dissection (SCAD) highlight how even subtle changes in multi-functional scaffold proteins can manifest …

L Azizi, Y Otani, VV Mykuliak, BT Goult… - Human Molecular …, 2024 - academic.oup.com
Abstract Variants of talin-1 (TLN1) have recently been linked with spontaneous coronary
artery dissection (SCAD) a condition where a tear can form in the wall of a heart artery …

[HTML][HTML] Paracellular barriers: Advances in assessing their contribution to renal epithelial function

S Jonusaite, N Himmerkus - … Biochemistry and Physiology Part A: Molecular …, 2024 - Elsevier
Regulation of salt and water balance occupies a dominant role in the physiology of many
animals and often relies on the function of the renal system. In the mammalian kidney …

[HTML][HTML] 3D fluorescence staining and imaging of low amount of organoids

AG Toulehohoun, C Bouzin, A Daumerie, L Maccioni… - 2024 - slack.protocols.io
The emerging field of 3D organ modeling encounters several imaging issues in particular
related to antigen retrieval and sample lost during staining processes. Due to their compact …