Asynchrony consequences and management

T Pham, I Telias, T Piraino, T Yoshida… - Critical Care …, 2018 - criticalcare.theclinics.com
Mechanical ventilation is the most common life support procedure in the intensive care unit
(ICU). 1 It is used in a full spectrum of acute situations, which share the same primary goals …

Beyond low tidal volume ventilation: treatment adjuncts for severe respiratory failure in acute respiratory distress syndrome

V Fielding-Singh, MA Matthay, CS Calfee - Critical care medicine, 2018 - journals.lww.com
Objectives: Despite decades of research, the acute respiratory distress syndrome remains
associated with significant morbidity and mortality. This Concise Definitive Review provides …

Intensive care unit-acquired weakness and hospital functional mobility outcomes following invasive mechanical ventilation in patients with COVID-19: a single-centre …

MN Núñez-Seisdedos, I Lázaro-Navas… - Journal of Intensive …, 2022 - journals.sagepub.com
Background: Acute physical function outcomes in ICU survivors of COVID-19 pneumonia
has received little attention. Critically ill patients with COVID-19 infection who require …

Improving prone positioning for severe acute respiratory distress syndrome during the COVID-19 pandemic. An implementation-mapping approach

T Klaiman, JA Silvestri, T Srinivasan… - Annals of the …, 2021 - atsjournals.org
Rationale: Prone positioning reduces mortality in patients with severe acute respiratory
distress syndrome (ARDS), a feature of severe coronavirus disease 2019 (COVID-19) …

Lessons to learn from epidemiologic studies in ARDS

BA McNicholas, GM Rooney… - Current Opinion in Critical …, 2018 - journals.lww.com
ARDS exerts a substantial disease burden, with 40% of patients dying in hospital. Diverse
factors, including patient-related factors such as age and illness severity, country level …

Factors influencing the implementation of prone positioning during the COVID-19 pandemic: a qualitative study

CH Hochberg, ME Card, B Seth, MP Kerlin… - Annals of the …, 2023 - atsjournals.org
Rationale: The adoption of prone positioning for patients with acute respiratory distress
syndrome (ARDS) has historically been poor. However, in mechanically ventilated patients …

[HTML][HTML] Comparing prone positioning use in COVID-19 versus historic acute respiratory distress syndrome

CH Hochberg, KJ Psoter, SK Sahetya… - Critical Care …, 2022 - journals.lww.com
Comparing Prone Positioning Use in COVID-19 Versus Historic... : Critical Care
Explorations Comparing Prone Positioning Use in COVID-19 Versus Historic Acute …

Neuromuscular blocking agents in acute respiratory distress syndrome: updated systematic review and meta-analysis of randomized trials

N Tarazan, M Alshehri, S Sharif, Z Al Duhailib… - Intensive Care Medicine …, 2020 - Springer
Purpose Existing clinical practice guidelines support the use of neuromuscular blocking
agents (NMBA) in acute respiratory distress syndrome (ARDS); however, a recent large …

Early use of adjunctive therapies for pediatric acute respiratory distress syndrome: a PARDIE study

CM Rowan, MJ Klein, DD Hsing… - American journal of …, 2020 - atsjournals.org
Rationale: Few data exist to guide early adjunctive therapy use in pediatric acute respiratory
distress syndrome (PARDS). Objectives: To describe contemporary use of adjunctive …

Patterns of use of adjunctive therapies in patients with early moderate to severe ARDS: insights from the LUNG SAFE study

A Duggal, E Rezoagli, T Pham, BA McNicholas, E Fan… - Chest, 2020 - Elsevier
Background Adjunctive strategies are an important part of the management of ARDS.
However, their application in clinical practice remains inconsistent. Research Question We …