Climate change and vectorborne diseases

MC Thomson, LR Stanberry - New England Journal of Medicine, 2022 - Mass Medical Soc
Climate Change and Vectorborne Diseases Warming temperatures and changes in
precipitation associated with climate change are affecting the occurrence of vectorborne …

A critical review on human malaria and schistosomiasis vaccines: current state, recent advancements, and developments

AJ Siddiqui, J Bhardwaj, J Saxena, S Jahan, M Snoussi… - Vaccines, 2023 - mdpi.com
Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of
morbidity and mortality worldwide. Co-infections of these two parasites are common in the …

[HTML][HTML] Increasing challenges of malaria control in sub-Saharan Africa: Priorities for public health research and policymakers

HJ Oladipo, YA Tajudeen, IO Oladunjoye… - Annals of Medicine and …, 2022 - Elsevier
The ever-increasing cases and mortality due to malaria remains one of the most important
public health threats, especially in sub-Saharan Africa—where this burden is considerably …

Medicinal plants used for treatment of malaria by indigenous communities of Tororo District, Eastern Uganda

JRS Tabuti, SB Obakiro, A Nabatanzi, G Anywar… - Tropical medicine and …, 2023 - Springer
Background Malaria remains the leading cause of death in sub-Saharan Africa. Although
recent developments such as malaria vaccine trials inspire optimism, the search for novel …

PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury

X Du, B Ren, C Li, Q Li, S Kan, X Wang, W Bai… - Nature …, 2024 - nature.com
Excessive host immune responses contribute to severe malaria with high mortality. Here, we
show that PRL2 in innate immune cells is highly related to experimental malaria disease …

Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum

M Lisauskaitė, GL Nixon, CM Woodley… - RSC Chemical …, 2024 - pubs.rsc.org
The emergence of Plasmodium parasite resistance to current front-line antimalarial
treatments poses a serious threat to global malaria control and highlights the necessity for …

Mechanistic insights into the interaction between the host gut microbiome and malaria

RK Mandal, NW Schmidt - PLoS Pathogens, 2023 - journals.plos.org
Malaria is a devastating infectious disease and significant global health burden caused by
the bite of a Plasmodium-infected female Anopheles mosquito. Gut microbiota was recently …

In Silico Approach Triterpene Glycoside of H. atra Targeting Orotidine 5‐Monophosphate Decarboxylase Protein (PfOMPDC) in P. falciparum Infection Mechanism

PD Utami, H Setianingsih… - BioMed Research …, 2024 - Wiley Online Library
This study accessed the potential antimalarial activity of triterpene glycoside of H. atra
through targeting orotidine 5‐monophosphate decarboxylase protein (PfOMPDC) in P …

Biphosphoglycerate mutase: A novel therapeutic target for malaria?

A Azzuolo, Y Yang, A Berghuis, N Fodil… - Transfusion Medicine …, 2023 - Elsevier
Biphosphoglycerate mutase (BPGM) is a tri-functional enzyme expressed exclusively in
erythroid cells and tissues that is responsible for the production of 2, 3-biphosphoglycerate …

Harnessing Leptolyngbya for antiproliferative and antimicrobial metabolites through lens of modern techniques: A review

R Negi, M Nigam, RK Singh - Algal Research, 2024 - Elsevier
Cancer and antimicrobial resistance are pressing global health concerns, with cancer
ranking as a foremost reason of death across the world, estimated to be about 10 million in …