Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD+-Dependent Enzymes and Plant-Derived Natural Products

A Iskander, LJ Yan - Biomolecules, 2022 - mdpi.com
Cisplatin is an FDA approved anti-cancer drug that is widely used for the treatment of a
variety of solid tumors. However, the severe adverse effects of cisplatin, particularly kidney …

[HTML][HTML] Butterfly pea flower (Clitoria ternatea L.) extract displayed antidiabetic effect through antioxidant, anti-inflammatory, lower hepatic GSK-3β, and pancreatic …

W Widowati, L Darsono, J Lucianus, E Setiabudi… - Journal of King Saud …, 2023 - Elsevier
Diabetes Mellitus (DM) is hyperglycemic or elevated blood glucose level and deficiency of
insulin level. DM treatment using synthetic drugs has several complexities, side effects …

[PDF][PDF] Protective Effect of Ethanolic Extract of Jati Belanda (Guazuma ulmifolia L.) by Inhibiting Oxidative Stress and Inflammatory Processes in Cisplatin-induced …

W Widowati, S Prahastuti, M Hidayat… - Pakistan Veterinary …, 2022 - pvj.com.pk
The accumulation of high concentrations of cisplatin in the kidneys may cause
nephrotoxicity. Cisplatin-induced nephrotoxicity happens through the inflammation of the …

Exploring the Role of Phenolic Compounds in Chronic Kidney Disease: A Systematic Review

F Baptista, J Paié-Ribeiro, M Almeida, AN Barros - Molecules, 2024 - mdpi.com
Chronic kidney disease (CKD) presents a formidable global health concern, affecting one in
six adults over 25. This review explores the potential of phenolic compounds in managing …

Enhancement of antioxidant activities in black soy milk through isoflavone aglycone production during indigenous lactic acid bacteria fermentation

BY Leksono, MN Cahyanto, ES Rahayu, R Yanti… - Fermentation, 2022 - mdpi.com
Black soybeans contain high antioxidant compounds such as isoflavone but mainly in
glucoside form, with low antioxidant activities. Fermentation by lactic acid bacteria (LAB) can …

Metabolite profiling, antidiabetic, and antioxidant potential of different tissues of Trillium govanianum Wall. ex D. Don

D Kumar, V Kumari - South African Journal of Botany, 2023 - Elsevier
Trillium govanianum Wall. ex D. Don (Melanthiaceae) is a medicinally important herbaceous
plant and its rhizomes are claimed to have therapeutic effects in traditional health practices …

Comparative assessment of nutritional metabolites in yellow soybeans at different growth years and their antioxidant and α-glucosidase inhibition properties

KM Cho, YM Lee, HY Lee, JH Lee - Agronomy, 2023 - mdpi.com
With regard to obtaining valuable information on the development of new breeding lines and
functional agents, the present study was the first to demonstrate variations in nutritional …

[HTML][HTML] Human Wharton's jelly mesenchymal stem cells inhibit cytokine storm in acute respiratory distress syndrome in a rat model

W Widowati, TL Wargasetia, F Rahardja… - Asian Pacific Journal …, 2022 - journals.lww.com
Objective: To evaluate the potential effect of human Wharton's jelly mesenchymal stem cells
(hWJMSCs) on acute respiratory distress syndrome in lipopolysaccharide (LPS)-induced …

Brazilin cream from Caesalpinia sappan inhibit periodontal disease: in vivo study

VK Sugiaman, J Jeffrey, S Naliani, N Pranata… - PeerJ, 2024 - peerj.com
Background Gingivitis is an inflammation of the gums that is the initial cause of the
development of periodontal disease by the activity of Nuclear Factor-kappa B (NF-κB) …

[HTML][HTML] Protective effect of yacon leaves extract (Smallanthus sonchifolius (Poepp.) H. Rob) through antifibrosis, anti-inflammatory, and antioxidant mechanisms …

W Widowati, R Tjokropranoto… - Research in …, 2023 - journals.lww.com
Background and purpose: Diabetic nephropathy (DN) is a chronic kidney failure, which may
lead to fatality. Mesangial cell proliferation, renal inflammation, stress oxidative, and fibrosis …