Astrocytes in fragile X syndrome

K Talvio, ML Castrén - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Astrocytes have an important role in neuronal maturation and synapse function in the brain.
The interplay between astrocytes and neurons is found to be altered in many …

Rescue of sharp wave-ripples and prevention of network hyperexcitability in the ventral but not the dorsal hippocampus of a rat model of fragile X syndrome

LJ Leontiadis, G Trompoukis, G Tsotsokou… - Frontiers in cellular …, 2023 - frontiersin.org
Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by
intellectual disability and is related to autism. FXS is caused by mutations of the fragile X …

Dysregulated acetylcholine-mediated dopamine neurotransmission in the eIF4E Tg mouse model of autism spectrum disorders.

J Carbonell-Roig, A Aaltonen, V Cartocci, A McGuirt… - bioRxiv, 2024 - biorxiv.org
Autism Spectrum Disorders (ASD) consist of diverse neurodevelopmental conditions where
core behavioral symptoms are critical for diagnosis. Altered dopamine neurotransmission in …

Dampened α7 nAChR activity contributes to audiogenic seizures and hyperactivity in a mouse model of Fragile X Syndrome

S Goebel, D Cordova-Martinez, VK Verselis… - bioRxiv, 2024 - biorxiv.org
Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability and
often accompanied with debilitating pathologies including seizures and hyperactivity. FXS …