Fetal programming of skeletal muscle development in ruminant animals

M Du, J Tong, J Zhao, KR Underwood… - Journal of animal …, 2010 - academic.oup.com
Enhancing skeletal muscle growth is crucial for animal agriculture because skeletal muscle
provides meat for human consumption. An increasing body of evidence shows that the level …

Maternal obesity and fetal metabolic programming: a fertile epigenetic soil

MJR Heerwagen, MR Miller… - American Journal of …, 2010 - journals.physiology.org
The incidence of obesity and overweight has reached epidemic levels in the United States
and developed countries worldwide. Even more alarming is the increasing prevalence of …

[PDF][PDF] Focus on obesity: Impact of maternal obesity on offspring obesity and cardiometabolic disease risk

AJ Drake, RM Reynolds - Reproduction, 2010 - scholar.archive.org
The prevalence of obesity among pregnant women is increasing. In addition to the short-
term complications of obesity during pregnancy in both mother and child, it is now …

Maternal environment and the transgenerational cycle of obesity and diabetes

D Dabelea, T Crume - Diabetes, 2011 - Am Diabetes Assoc
The prevalence of obesity continues to increase worldwide and represents one of the most
press-ing public health issues due to its associated morbidity, mortality, and health care …

AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression

X Sun, Q Yang, CJ Rogers, M Du, MJ Zhu - Cell Death & Differentiation, 2017 - nature.com
Impairment in gut epithelial integrity and barrier function is associated with many diseases.
The homeostasis of intestinal barrier is based on a delicate regulation of epithelial …

Does skeletal muscle have an 'epi'‐memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise

AP Sharples, CE Stewart, RA Seaborne - Aging cell, 2016 - Wiley Online Library
Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle
performance, maintaining metabolic function and supporting longevity and healthspan …

Developmental programming in response to maternal overnutrition

MZ Alfaradhi, SE Ozanne - Frontiers in genetics, 2011 - frontiersin.org
Metabolic disorders have seen an increased prevalence in recent years in developed as
well as developing countries. While it is clear lifestyle choices and habits have contributed to …

Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations

UD Wankhade, Y Zhong, P Kang, M Alfaro… - PloS one, 2017 - journals.plos.org
Objective Non-alcoholic fatty liver disease (NAFLD) is an important co-morbidity associated
with obesity and a precursor to steatohepatitis. However, the contributions of gestational and …

Nutritional programming of the metabolic syndrome

ME Symonds, SP Sebert, MA Hyatt… - Nature Reviews …, 2009 - nature.com
The primary markers of the metabolic syndrome are central obesity, insulin resistance and
hypertension. In this review, we consider the effect of changes in maternal nutrition during …

Intermuscular and intramuscular adipose tissues: Bad vs. good adipose tissues

GJ Hausman, U Basu, M Du, M Fernyhough-Culver… - Adipocyte, 2014 - Taylor & Francis
Human studies of the influence of aging and other factors on intermuscular fat (INTMF) were
reviewed. Intermuscular fat increased with weight loss, weight gain, or with no weight …