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Editor and the authors' response. The original version (PDF) is appended to this article as a …

Introduction: Sepsis, a dysregulated host response to infection, is a major cause of morbidity
and mortality worldwide. Early identification and evidence-based treatment of sepsis are …

Importance In October 2015, the Centers for Medicare & Medicaid Services began requiring
US hospitals to report adherence to the Severe Sepsis and Septic Shock Early Management …

Early IV fluid administration remains one of the modern pillars of sepsis treatment; however,
questions regarding amount, type, rate, mechanism of action, and even the benefits of fluid …

The last 50 years have been marked by increased understanding of the underpinnings of
sepsis, its myriad manifestations and optimal approaches to therapy. The 50-year timeline …

Study objective To test the hypothesis that provider-to-provider tele-emergency department
care is associated with more 28-day hospital-free days and improved Surviving Sepsis …

Background: In 2018, the Centers for Medicaid and Medicare Services (CMS) issued a
protocol for the treatment of sepsis. This bundle protocol, titled SEP-1 is a multicomponent 3 …

Even well-intentioned policies have great potential to cause harm. This statement is vividly
illustrated by the influential, yet controversial, Surviving Sepsis Campaign (SSC) guidelines …

The last 30 years have seen major progress in our understanding and treatment of asthma.
Perhaps the most important single advance was the recognition that a chronic, often …

Abstract The 'Sepsis Six'bundle was promoted as a deliverable tool outside of the critical
care settings, but there is very little data available on the progress and change of sepsis care …