Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …

Chronic pain is an important public health problem, and there is a need to understand the
mechanisms that lead to pain chronification. From a neurobiological perspective, the …

In vivo 1 H MR spectroscopic detection of pain associated metabolic changes in the human
brain may allow for an objective evaluation of the perceived pain intensity and assessment …

Transcranial Direct Current Stimulation (tDCS) is a method of non-invasive brain stimulation
that has been frequently used in experimental and clinical pain studies. However, the …

Background In clinical practice, analgesic drug doses applied during general anaesthesia
are considered sufficient when clinical responses (eg movement, blood pressure and heart …

Migraine is underpinned by central nervous system neuroplastic alterations thought to be
caused by the repetitive peripheral afferent barrage the brain receives during the headache …

Arterial spin labeling (ASL) sequences that incorporate multiple postlabeling delay (PLD)
times allow estimation of when arterial blood signal arrives within a region of interest …

Recent neuroimaging studies implicate the medial temporal lobe (MTL) in nociception and
pain modulation. Here, we aim to identify which subregions of the MTL are involved in …

The search for a “pain centre” in the brain has long eluded neuroscientists. Although many
regions of the brain have been shown to respond to painful stimuli, all of these regions also …

Arterial spin labelling (ASL) is increasingly being applied to study the cerebral response to
pain in both experimental human models and patients with persistent pain. Despite its …