There are currently more than 600 diseases characterized as affecting the central nervous
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …

The spinal cord is the primary neurological link between the brain and peripheral organs.
How important it is in everyday life is apparent in patients with spinal cord injury or …

Excessive excitation is hypothesized to cause motoneuron (MN) degeneration in
amyotrophic lateral sclerosis (ALS), but actual proof of hyperexcitation in vivo is missing, and …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder.
Separate lines of evidence suggest that synapses and astrocytes play a role in the …

Cannabinoids reduce tremor associated with motor disorders induced by injuries and
neurodegenerative disease. Here we show that this effect is mediated by cannabinoid …

Fluorescent lipophilic dyes, such as DiI, stain cellular membranes and are used extensively
for retrograde/anterograde labeling of neurons as well as for marking the position of …

Key points GABA is an essential molecule for sensory information processing. It is usually
assumed to be released by neurons. Here we show that in the dorsal horn of the spinal cord …

The assessment, management, and prognostication of spinal cord injury (SCI) mainly rely
upon observer-based ordinal scales measures. 1H nuclear magnetic resonance (NMR) …

Evidence suggests that astrocytes are not merely supportive cells in the nervous system but
may actively participate in the control of neural circuits underlying cognition and behavior. In …

Functionally distinct synapses exhibit diverse and complex organisation at molecular and
nanoscale levels. Synaptic diversity may be dependent on developmental stage, anatomical …